I'm selecting the pipette tips to use in our new lab. We are going to buy bulk tips and use them after autoclaving them. I found that some products are described as "pyrogen-free" and some are not. They are more expensive, and also, the tips I tried and liked the shape were not pyrogen-free. It sounds better to be "anything"-free which means less contamination, but should all the tips be pyrogen-free? If they are not stated as pyrogen-free, are they actually contaminated with pyrogen and likely to cause troubles in our experiments?
Thank you in advance.
Daisuke Koga
Yes, all pipette tips used in laboratory settings, especially in biomedical and pharmaceutical applications, should be pyrogen-free. Pyrogens are substances, usually of bacterial origin, that can cause undesirable reactions in the body, such as temperature and inflammatory reactions.
When performing experiments or tests that require a high level of purity, it is important that all tools, including pipet tips, are pyrogen-free.
Therefore, when choosing pipette tips, it is important to check whether they are labeled as "pyrogen-free" or "pyrogen-free" to ensure quality control and safety of results.
Dragan Ugrinov Thank you! I will make sure that all the pipette tips are pyrogen-free.
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