Hi Manash,

you can e-mail your question to:

Jeffrey Salisbury

[email protected]

Dr. Salisbury is expert in this area, he will love to answer your question,

Best

thanks Subhash,

I will definitely contact him.

Best wishes

Most motile cilia also have signalling receptors on their surfaces, and so function just like non-motile primary cilia. Most mammalian motile cilia are only on multi-ciliated cells that express factors such as MCIDAS during their differentiation. An exception is the monociliated cells of the embryonic node, which assemble single motile cilia, and sperm with single motile flagella.

In general, primary cilia express receptors specific to the cell type, rather than specific to all primary cilia, and cells that have only primary cilia (with the exception of the nodal cilia discussed above) fail to express genes for the hundreds of proteins needed for motility (axonemal dynein subunits, radial spoke subunits, etc.).

Thank you Prof. Mitchell. Really appreciate your inputs. You are a pioneer in this field.