ISUIA study showed that unruptured aneurysm located in posterior circulation has a higher risk of rupture than other location. Does anyone know any theory could support/refute to this result (anatomical, physical, hemodynamic...)?
Joonho Chung
There is a theory supporting the result anatomically as well as hemodynamically.
Simply, posterior circulation has no intracranial siphon (only have extra cranial siphon in V3 segment) whereas the internal carotid artery has intracranial siphon (cavernous segment-to-ophthalmic segment). It is much more straight than anterior circulation. Thus, aneurysms in posterior circulation recieve more hemodynamic stressr than those in anterior circulation.
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