Phytosomes to target and treat cancer tissues

More Renuka devi J's questions See All

Can we patent a drug moiety arising out of natural product research?

Hi All We are involved in natural product drug research involving activity guided fractionation, structural characterisation and insilico science. I request your guidance in the patenting norms...

09 October 2018 9,992 0 View

How to interpret the nmr and mass spectral data?

Dear All Please guide me how to interpret the structure of phytoconstituent from crude extract of natural product sequentially Is there any online available tools to interpret the data

11 December 2016 3,928 3 View

How to optimize plant fraction for anti inflammatory potential?

Hi all I wish to optimise my antiinflammatory fraction of plant to successful lead against inflammation, After separation and optimisation insilico how to progress with and invivo evaluation of...

08 September 2016 650 3 View

How to assess the synergism/antagonism in plant extract?

Hi all I want to assess the synergism/additive/antagonism of individual fractions of plant extract, Is there any alternative methods other than isobolographic analysis? Kindly help me in this regard.

08 September 2016 970 3 View

Synthesis /Semisynthesis of natural product ? Design of synthesis procedure for natural product

Hi All I want to test my isolated phytoconstituent for some biological activity( i.e antidiabetic or anticancer).How to screen individual phytoconstituent or the synthetic analog is potent?. How...

03 April 2016 6,240 4 View

How to study the 3D QSAR modelling of phytoconstituents in Accelyrs Discovery studio?

Dear All We are doing pharmacophore modelling of our phytoconstituents from Brassica sps in Accelyrs Discovery studio. Kindly guide me in doing 3D QSAR modelling in Accelyrs discovery studio.

02 March 2016 5,439 0 View

Can we study the anticancer activity of two phytoconstituents (in combination) to treat inflammation/cancer in cell lines/animal models ?

Hi All I am planning to study the molecular mechanism that link inflammation and cancer. I request you to advice me that whether two phytoconstituents(which share same biological property) can be...

02 March 2016 10,096 4 View

How to quantify vitamins in plant extracts

Quantification and identification of vitamin in plant extract How to quantify vitamins such as A D E K in plant extracts?

01 February 2016 5,925 4 View

Quantification and identification of vitamin in plant extract How to quantify vitamins such as A D E K in plant extracts?

Your toughest technical questions will likely get answered within 48 hours on ResearchGate, the professional network for scientists.

07 August 2015 1,158 0 View

Can we patent a drug moiety arising out of natural product research?

Hi All We are involved in Natural Product Research.Can we patent a lead drug moiety arising out of Natural Product Research. Regds J Renuka

01 January 1970 9,947 15 View

Radiogenomics Cancer Research Challenges?

what are the top 3 challenges to the advancement of the field of Radiogenomics in cancer research? is it the availability of easily available low-cost matched imaging and biosamples with clinical...

03 August 2024 5,828 4 View

For a case-control study for Breast Cancer incidents in a particular County in USA, what data can be used as Control? E.g. colorectal cancer?

The County health department is providing Breast cancer incident data. If colorectal cancer cases could be used as control, then we can get respective data from health department as well.

22 July 2024 9,954 4 View

About Machine Learning for Automated Diagnosis of Skin Cancer with Dermoscopy Images ?

Machine Learning for Automated Diagnosis of Skin Cancer with Dermoscopy Images

21 July 2024 5,471 0 View

Fixation Problem with cancer cells?

Hello everyone, I work with polyacrylamide hydrogels, which I fictionalise with sulfo-sanpa and collagen I to then plate lung cancer cells. The problem is that I lose a significant amount of...

19 July 2024 3,906 0 View

Does anyone notice the tumor regression impact of Hepa1-6 cells in HCC orthotopic mice model?

To establish an orthotopic HCC model, C57BL/6 mice (male, 6-8 weeks) were orthotopically implanted with 3x106 Hepa1-6 cells (Over-expressed with a human gene) in 20uL Matrigel into the left lobe...

18 July 2024 9,177 2 View

How to prepare bacterial conditioned media to study the effect of bacterial secretome?

I would like to investigate the effect of bacterial secretome on cancer cells. How do you prepare conditioned media from bacteria?? conditions- time points - media I am looking for the best way...

17 July 2024 3,785 9 View

Contaminant cells in pancreatic cancer patient derived organoids?

Hello everyone, I am cultivating patient derived organoids from pancreatic cancer patients and I saw at the bottom of my domes some "strange" cells other than my usual organoids. I know I should...

15 July 2024 762 3 View

Oncologist at Visakhapatnam interested to collaborate?

Calling all medical professionals and researchers! I'm seeking recommendations for an oncologist in Visakhapatnam who can collaborate on my PhD thesis. My research focuses on stage 1 and 2 gastric...

14 July 2024 936 0 View

What factors could be contributing on low tumor take in female Nude mice?

Hello everyone, I'm working with a PA-1 ovarian cancer cell line xenograft model in female nude mice. My cells are at 372 passages, the cell repository bank themselves gave at 352th passage....

05 July 2024 5,860 1 View

WST-1 test for 3D cell culture?

I want to perform WST-1 test with alginate based 3D-colorectal cancer cells. I wonder about before performing WST-1 test, ıs it necessary to remove alginate spheres from the cells (to carry it...

29 June 2024 9,667 1 View