Can we patent a drug moiety arising out of natural product research?

Hi All We are involved in natural product drug research involving activity guided fractionation, structural characterisation and insilico science. I request your guidance in the patenting norms...

09 October 2018 9,839 0 View

How to interpret the nmr and mass spectral data?

Dear All Please guide me how to interpret the structure of phytoconstituent from crude extract of natural product sequentially Is there any online available tools to interpret the data

11 December 2016 3,727 3 View

How to optimize plant fraction for anti inflammatory potential?

Hi all I wish to optimise my antiinflammatory fraction of plant to successful lead against inflammation, After separation and optimisation insilico how to progress with and invivo evaluation of...

08 September 2016 499 3 View

How to assess the synergism/antagonism in plant extract?

Hi all I want to assess the synergism/additive/antagonism of individual fractions of plant extract, Is there any alternative methods other than isobolographic analysis? Kindly help me in this regard.

08 September 2016 807 3 View

Synthesis /Semisynthesis of natural product ? Design of synthesis procedure for natural product

Hi All I want to test my isolated phytoconstituent for some biological activity( i.e antidiabetic or anticancer).How to screen individual phytoconstituent or the synthetic analog is potent?. How...

03 April 2016 5,933 4 View

Can we study the anticancer activity of two phytoconstituents (in combination) to treat inflammation/cancer in cell lines/animal models ?

Hi All I am planning to study the molecular mechanism that link inflammation and cancer. I request you to advice me that whether two phytoconstituents(which share same biological property) can be...

02 March 2016 9,949 4 View

How to study the 3D QSAR modelling of phytoconstituents in Accelyrs Discovery studio?

Dear All We are doing pharmacophore modelling of our phytoconstituents from Brassica sps in Accelyrs Discovery studio. Kindly guide me in doing 3D QSAR modelling in Accelyrs discovery studio.

02 March 2016 5,238 0 View

How to quantify vitamins in plant extracts

01 February 2016 5,742 4 View

Phytosomes to target and treat cancer tissues

Sir Can we use phytosomes to target, treat and sensitise cancer tissues?

01 February 2016 9,389 3 View

Can we patent a drug moiety arising out of natural product research?

Hi All We are involved in Natural Product Research.Can we patent a lead drug moiety arising out of Natural Product Research. Regds J Renuka

01 January 1970 9,786 15 View

What are the most reliable approaches to extract key continuous frames from a video, with complete automation?

I have an input video, of skin (from a microscope that means it is magnified such that blood capillaries are visible). The idea is to extract 15 sec of continuous frames from a video of 1 min,...

02 March 2021 2,735 2 View

How to quantitative analize the data of TNBS assay for gelatin?

Estemeed colleagues, I found some issues regarding the quantification of the data for TNBS assay. There are different protocols on how to perform that but it is clear to me the "fil rouge" that...

02 March 2021 2,616 1 View

Which is the best place in the world for the plant biotechnology research?

I am searching for a good place for the Post Doc,

02 March 2021 4,053 3 View

How can extract ciprofloxacin hydrochloride disolve in water er to organic solvent such as dichloromethan or any other solvent?

I need a procedure to extract the ciprofloxacin hydrochloride from aqueous solution by using dichloromethane in detail,. I thank you very much.

01 March 2021 4,306 1 View

Which bacteria are suitable for quorum sensing screening?

I want to find a quorum sensing inhibitor from plant extracts. Klebsiella pneumoniae, Moraxella catarrhalis, Staphylococcus aureus, and Streptococcus pneumoniae. I looked for these strains...

01 March 2021 7,675 3 View

Isolates of Hymenoscyphus fraxineus?

Dear Dr. Cai, my name is Simone Prospero and I work in the team of Phytopathology at the Swiss Federal Institute for Forest Snow and Landscape Research (WSL;...

01 March 2021 1,133 1 View

How to accurately quantify chitin?

Hi all, I have been working on the quantification of chitin in insect samples and feed for a while but I can notice that the quantification methods (e.g. exposure to HCl, NaOH, and weighing sample...

01 March 2021 1,843 2 View

How to perform statistical analysis of coefficients extracted from transform techniques?

I am studying the potential of DCT and FFT coefficients extracted from a signal to classify the different objects that emit the signal. I applied the Shapiro-Wilk to confirm that data was not...

01 March 2021 8,079 2 View

Where to find data on trees in tropical agroforestry?

Hi, I'm looking for data (mainly related to management: growth rate, canopy size, soil and climate preferences, etc.) about tropical trees used in tropical agroforestry. Have you ever heard about...

28 February 2021 7,356 8 View

How to remove fatty material from plant extract?

The resultant solid was partitioned three times with 250 ml of petroleum ether (40-60/c) to remove any fatty material and evaporated to dryness.

28 February 2021 9,464 2 View