PDGFRa can be applied for both normal and cancer-associated fibroblasts? If yes, which markers could be specifically used for each phenotype?

Marconi Rego Barros Jr @Marconi-Rego-Barros-Jr

16 May 2018 0 6K Report

I have found in literature that PDGFRa is used as a CAFs (cancer-associated fibroblasts) marker, but does this receptor also mark normal fibroblasts? Which markers could be used for each fibroblast phenotype in case someone wants to evaluate one at a time?

Badges
Science topic

More Marconi Rego Barros Jr's questions See All

How to create the context-mechanism-outcome configuration (CMOc) in the realist methodology?

In the realist methodology (especially by Raymond Pawson et al), the CMOc is a common structure to explain what works, for whom, in what circumstances, and why? I'm always asked about the...

08 February 2021 2,792 1 View

What could cause a loss of detector response for a brief period of time in UHPLC/MS?

The following have already been done, 1. Solvent change and fresh new samples were prepared.

03 December 2020 8,532 1 View

What utility function would be used to reward/punish learning of non local rules defining implicate order?

Given the Meijer paper "A New Premise for Quantum Physics, Consciousness and Fabric of Reality," I am developing an OpEMCSS systems science simulation model. The system is a network of concurrent...

23 November 2020 6,493 1 View

Professional Engineer's Code of Ethics: What & How To Assure Compliance?

Historically, the subject question has been met mainly with "After The Fact" assertions. Yet when one learns of the infrastructure failures . . .bridges, tunnels, pipelines, highways. . . it...

11 November 2020 3,574 3 View

There is a GLMM for proportion structure data?

I would like to ask a recommendation of a statistical test to answer a question related to an unusual data structure. I am testing if birds change nest parental care behavior depending on...

17 October 2020 2,026 1 View

Hello everyone, good day! In the process of deproteinization of samples to obtain chitin, can I make use of a phenol as a deproteinizing agent?

I would like to know what other reagents can be used to obtain chitin by deproteinizing a sample. Commonly found on articles is the employment of NaOH concentrations as well as KOH. I would like...

16 October 2020 537 6 View

What do you think are the factors affecting the Online Collaborative Approach of the teachers in today's situation?

This is research-related question.

05 October 2020 4,606 4 View

Q1. What changes have been observed in the professional lives of our CE graduates ? Q2. What CE academic programs have developed?

In June 1995, the culmination of some 3 years or so of preparation, led by professor Dr. Jim Yao, Texas A&M, resulted in an "ASCE Education Conference" in Denver, CO. At the end of that...

12 August 2020 1,069 3 View

What Solvent is appropriate for DPPH when extracting with ethanol?

I am working with seaweeds. I am using using ethanol as my extraction solvent based on preliminary experiment and using methanol to dissolve my DPPH, should I expect any difference than, when I...

09 July 2020 1,052 14 View

How to teach qualitative research among students/participants who are highly quantitative in perspective?

Students/participants who always use measurement or numbers in understanding all phenomena may require more effort in convincing them about the importance and processes of qualitative research.

09 July 2020 7,831 26 View

What's the best way to measure growth rates in House sparrow chicks from day 2 to day 10?

What's the best way to measure growth rates in House sparrow chicks from day 2 to day 10? Since, the growth curve from day 2 to 10 won't be like the "Logistic curve" it might not follow logistic...

03 March 2021 1,401 3 View

Is SSRN e-Journal Scopus indexed?

I have publication in SSRN. I want to know whether it is Scopus indexed? Does it show impact factor? What is its ISSN No.?

02 March 2021 4,565 3 View

Does Napabucasin soluble in dichloromethane and in ethanol?

I need to prepare a solution of Napabucasin (inhibitor of cancer cell stemness) in dichloromethane. The drug is expensive, so maybe somebody already tried to do it. If it is soluble, what is the...

02 March 2021 9,945 3 View

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

01 March 2021 8,087 3 View

Which cell line should we use to perform biological dosimetry experiments?

We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...

01 March 2021 3,355 3 View

What is the most reliable source to get Impact factor of journals?

Source to get Impact factor of journals

01 March 2021 6,654 2 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

How to add missing citation?

Dear colleagues, I have found that many authors have a concern regarding their missing citation in RG because often citation in RG is lower than google scholars. I also missed some citation...

26 February 2021 928 6 View

Is IMPACT FACTOR justified in case of Taxonomy?

There is huge pressure of getting good impact factor on scholars now a days. On the other hand Taxonomy is a very dry subject and the concerned papers can only get citation in same group of organism.

26 February 2021 5,851 1 View

Does RNAiMAX transfection reagent work in serum free medium?

I diluted siRNA and RNAiMAX in opti-MEM and added to the cells which they were in the growth medium. Is it a right way? or should I culture cells in the opti-MEM medium for a while and not in...

26 February 2021 10,041 3 View