Hi everybody, I'm currently working on somatic mutations at diagnosis in leukemia with a panel of 81 genes tested at diagnosis (I have data on the type of mutation, the VAF and there is also copy number variation evaluation) of 70 patients. How do you suggest to organize data in excel to evaluate them? which graphics do you suggest to realize?
This is the first time that I manage NGS results with a panel of 81 genes + CNV and I'm a little lost.
Thank you.
Hi
You might choose some simple software for analyses such as minitabs or spss if you dont have any programming skills. For the best, you might use R to do it, and it has many graphic options.
Best
Hi colleague
Find the following URL may help you:
Article Comprehensive genetic diagnosis of acute myeloid leukemia by...
Regards...
Hi Matteo. Welcome to the field of NGS bioinformatics. Do you have any skills in R or other graphically strong programming environments, such as mathematica? I have previously chosen to display such data in a heatmap like fashion, where the VAF is color-coded, genes on one axis and patients on the other. You can write to me on [email protected] or [email protected] if you need some more ideas.
Thank you all.
Marcus, I'm going to write to you an email, thank you!
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