Many published studies showed the role of Neutrophil Elastaste (NE) in sputum to bronchiectastic patients. NE in sputum or BAL could present neutrophil inflammation on airways of bronchiectastic patients but why we do not use the count of neutrophil in sputum or BAL to prognosis for those patients?
Thanks for your help.
The topic you propose would make a really valuable publication. I'm not aware of the differences in prognosis of bronchiectasis patients, but in that case, it's important to show that neutrophil counts or a threshold correlate with disease activity and prognosis. Sometimes the diagnosis of bronchiectasis or its cause could be sufficient to estimate the prognosis, that is, neutrophil count in sputum might be unnecessary. But it would be a valuable investigation and to carry out the corresponding sensitivity vs 1-specificity plots (ROC curves).
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