Citations descending and ascending order by RG?

It seems to me that it would be extremely useful for the RG members to be able to have their citations by descending and ascending order much like Scopus. Companies can use this added criterion...

01 February 2018 2,578 0 View

Should the identity of the reviewer be made in the title page of the publication?

Reviewers perform an important role that results in the improved quality of a publication. However, with the exception of a few proceedings and books, they are not identified in the peer reviewed...

06 July 2013 3,294 42 View

Will nano antibodies directed against exposed TolC antigens of the RND efflux pump system inhibit efflux pump activity responsible for mdr phenotypes?

RND efflux pumps of Gram-negative bacteria bestow an MDR phenotype. Because deletion of the AcrAB-TolC main efflux pump of E. coli promotes the over-expression of the AcrEF-TolC as well as 8...

05 June 2013 7,243 0 View

Are efflux pumps of bacteria the means by which all secretions from the bacterium take place?

The first response of bacteria to a noxious agent such as an antibiotic is the induced over expression of efflux pumps. Once the threat of the noxious agent passes, the level of efflux pump...

05 June 2013 9,113 5 View

Should doctoral students of biomedical areas form an international society that supports their needs?

Doctoral students have needs that are not readily addressed by their mentors (supervisors). What are your needs as a doctoral student in your country and would the creation of an international...

04 May 2013 6,534 4 View

Are there any cancer cell lines that express more than one efflux pump responsible for the MDR phenotype of the cell?

Normal cells human cell types express different ABC transporters that when over expressed in the cancer cell render the cancer cell with an MDR phenotype. However, the genome of the normal cell...

04 May 2013 1,400 8 View

Besides novobiocin and chlorpromazine, are there other compounds that cure bacteria of plasmids?

A specific concentration of chlorpromazine eliminates plasmids from bacteria as a consequence of inhibiting plasmid replication whereas replication of the bacterial genome is unaffected. The...

04 May 2013 939 2 View

Can specific lasers matched to the energy level of a molecule create new molecules not readily made by conventional organic chemistry methods?

We have exposed a number of bioactive pure compounds to lasers of a given nm wavelength and energy level for varying periods of time, followed the result of exposure via thin layer chromatography,...

04 May 2013 6,594 1 View

Why does blocking with my immunogenic peptide cause nuclear fluorescence in ICC?

Hi all, I am validating a polyclonal antibody raised against human ANT4, through WB and ICC. In most of my controls, the antibody shows very little off-target binding, but when I pre-incubate the...

03 March 2021 5,999 3 View

Does Napabucasin soluble in dichloromethane and in ethanol?

I need to prepare a solution of Napabucasin (inhibitor of cancer cell stemness) in dichloromethane. The drug is expensive, so maybe somebody already tried to do it. If it is soluble, what is the...

02 March 2021 9,945 3 View

Help request in CST microwave?

im working now on TPV solar cells and metamaterials and i realy need our help in CST microwave i have a tpv cell simulation and i want to extract particullarly the absorbtion of only the active...

02 March 2021 2,246 2 View

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

01 March 2021 8,087 3 View

Which cell line should we use to perform biological dosimetry experiments?

We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...

01 March 2021 3,355 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

Dapi fluorescence protocol for colon cell lines ?

28 February 2021 2,534 2 View

Does RNAiMAX transfection reagent work in serum free medium?

I diluted siRNA and RNAiMAX in opti-MEM and added to the cells which they were in the growth medium. Is it a right way? or should I culture cells in the opti-MEM medium for a while and not in...

26 February 2021 10,041 3 View

Has anyone had luck using cell lines other than HEK 293 (such as COS1) to package lentivirus?

I am looking to package lentivirus in endothelial cells but I am opposed to using 293 cells due to personal ethics regarding the source. I have done some reading and saw that COS1, COS7, & CHO...

25 February 2021 3,030 1 View

Unknown debris sheets observed in cell culture flasks?

Hi, We culture neural progenitor cells in T175 culture flasks coated with PLO-Laminin. We have successfully grown these cells with our protocol for months. Recently, we observed large sheets...

25 February 2021 3,443 4 View