MicroRNA designing by bioinformatics tools?

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Satyajeet Khare

Do you mean siRNA? You can look into literature. You may find siRNA that is already designed for Stat3 in the species of your interest. Here is a review on siRNA and miRNA. Here are guidelines for siRNA design. There are some online tools that can help.

http://www.nature.com/mtna/journal/v4/n9/full/mtna201523a.html

https://www.thermofisher.com/in/en/home/references/ambion-tech-support/rnai-sirna/general-articles/-sirna-design-guidelines.html

https://rnaidesigner.thermofisher.com/rnaiexpress/

Mokhtar Nosrati

Thank you for your attention, I mean is micRNA.

Hossein Tabatabaeian

Hi,

If you mean finding a microRNA which targets stat3 mRNA, I recommend miRWalk 2.0 online tool. It integrates many algorithms together so that you can choose a microRNA which is common among all database.