Dear all,
Are there any mice strain available which are deficient specifically in group 3 or group 2 ILCs?
best,
Arshed
Have you checked with the Jackson Lab?
Hi,
Yes I checked Jackson but, couldn't find any.
Hello,
Marco Colonna's group has generated an ILC3-deficient mouse in a RAG2-/- background. They published an article using it:
Unique and redundant functions of NKp46+ ILC3s in models of intestinal inflammation.
Song C, Lee JS, Gilfillan S, Robinette ML, Newberry RD, Stappenbeck TS, Mack M, Cella M, Colonna M.
J Exp Med. 2015 Oct 19;212(11):1869-82
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