The compound Drosophilin A is known to have antibacterial and antifungal activity (Anchel et al. 1955; Anchel 1952; Kavanagh et al. 1952). Its methylated analog, Drosophilin A methyl ether, also a fungal metabolite (Teunissen 1999), has no reported -as far as i know- any biological activity.
- DA IUPAC Standard InChIKey: XIWJLPHQDBDOAN-UHFFFAOYSA-N
- DAME IUPAC Standard InChIKey: HICARXIPJINIRA-UHFFFAOYSA-N
- Anchel 1952: bit.ly/2DpFB2U
- Kavanagh et al. 1955: bit.ly/2FBypU7
- Anchel et al. 1955: bit.ly/2PuxBVA
- Teunissen 1999: bit.ly/2FpkC2M
Chemical structures from NIST Chemistry WebBook, SRD 69
There is report that the lignicolous basidiomycete Phellinus badius deposits up to 30,000 mg of the halogenated metabolite drosophlilin A methyl ether ( DAME, tetrachloro-1,4 dimethoxybenzene ) per kilogram of decayed hearthwood in the mesquite Proscpis julifora.. DAME occurs as clusters of glassy crystals up 1 mm long within the decayed heartwood. For more details consult The Science of Nature 102(3-4): 18 DOI: 10.1007/s00114-015-1268-5
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