Are there any fluorescently labeled anti-Alpaca secondary antibodies raised in Donkey? So far I have only been able to find anti-Alpaca secondaries raised in Goat.
Or is this not possible due to high similarity between donkeys and camelids?
Best, Niko
Based on the search results, it appears that commercially available anti-Alpaca secondary antibodies raised in Donkey are not commonly found. The search results primarily mention the availability of anti-Alpaca secondary antibodies raised in other host species such as Goat.
However, there are alternative options mentioned in the search results. One option is the use of secondary antibodies produced in Alpaca itself. These secondary antibodies exhibit minimal cross-reactivity with camelid-derived antibodies and can be used in multiple labeling assays.
Jackson ImmunoResearch offers alpaca secondary antibodies that are prepared to ensure minimal cross-reactivity with bovine serum proteins. Additionally, the search results mention the use of Llama antibodies, which belong to the same family as Alpaca (Camelidae). Llama-derived antibodies, including nanobodies, have benefits for certain applications such as super-resolution imaging.
While there is no specific mention of the high similarity between donkeys and camelids as a reason for the lack of commercially available donkey anti-Alpaca secondary antibodies, it is possible that the availability is influenced by factors such as cross-reactivity and the suitability of different host species for specific applications.