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prevention is better than cure.
At this time, there are no specific vaccines or treatments for COVID-19. However, there are many ongoing clinical trials evaluating potential treatments.
U.S. President Donald Trump announced on March 19 that chloroquine (hydroxychloroquine / Plaquenil), a drug used to treat malaria and arthritis, had been approved by the U.S. Food and Drug Administration (FDA) to be tested as a treatment for COVID-19. But yet, they are under clinical researches.
In China, the National Administration of Medicinal Products has approved the use of favelavir, an antiviral drug, as a treatment for coronavirus. The drug was reported to be effective in treating the disease with minimal side effects in a clinical trial involving 70 patients. The clinical trial is taking place in Shenzhen, Guangdong Province.
At this time, there are no specific vaccines or treatments for COVID-19. However, there are many ongoing clinical trials evaluating potential treatments.
Currently there is no any approved drug or vaccine for coronavirus (COVID-19). Therefore, staying home, consuming immunity strengthening foods, and maintaining good personal hygiene are important to avoid the risk of disease.
The situation of COVID19 in N. Italy is out of control and it is more compatible with MERS / SARS. New treatments are urgent >>> https://www.researchgate.net/post/The_novel_Coronavirus_in_N_Italy_Lombardia_COVID19_2019nCoV_SARSCoV2_shows_a_fatality_rate_compatible_with_SARS_Why2
There is no any effective vaccine against tis virus yet. Actually, we hope that the scientists quickly find a suitable drug to control this pandemic disease.
Hydroxy Chloroquine is declared as one of the treatment at early stage only in India . But in serious stage it will be not the treatment . Some pipeline drugs like
Higher generation synthetic drug of aciclovir is FLAVIVILAVIR ( The drug under
pipeline ) will be most effective - under Chinese R & D .
The Prophet Muhammad stated that a nigella sativa is a treatment for every disease and this is my source that I wanted to benefit human beings. The benefits of a nigella sativa for the respiratory system and the immune system can be looked for to be sure in many references.
At the moment, a number of investigational agents are being explored for antiviral treatment of COVID-19, however there are no controlled data supporting the use of any of these agents, and their efficacy for COVID-19 is unknown.
● Remdesivir – Several randomized trials are underway to evaluate the efficacy of remdesivir for moderate or severe COVID-19 . Remdesivir is a novel nucleotide analogue that has activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in vitro and related coronaviruses (including SARS and MERS-CoV) both in vitro and in animal studies. The compassionate use of remdesivir through an investigational new drug application was described in a case report of one of the first patients with COVID-19 in the United States. Any clinical impact of remdesivir on COVID-19 remains unknown.
● Chloroquine/hydroxychloroquine – Both chloroquine and hydroxychloroquine have been reported to inhibit SARS-CoV-2 in vitro, although hydroxychloroquine appears to have more potent antiviral activity .
Use of chloroquine is included in treatment guidelines from China's National Health Commission and was reportedly associated with reduced progression of disease and decreased duration of symptoms. However, primary data supporting these claims have not been published.
Other published clinical data on either of these agents are limited. In an open-label study of 36 patients with COVID-19, use of hydroxychloroquine (200 mg three times per day for 10 days) was associated with a higher rate of undetectable SARS-CoV-2 RNA on nasopharyngeal specimens at day 6 compared with no specific treatment (70 versus 12.5 percent) . In this study, the use of azithromycin in combination with hydroxychloroquine appeared to have additional benefit, but there are methodologic concerns about the control groups for the study, and the biologic basis for using azithromycin in this setting is unclear.
Despite the limited clinical data, given the relative safety of short-term use of hydroxychloroquine, the lack of known effective interventions, and the in vitro antiviral activity, some clinicians think it is reasonable to use hydroxychloroquine or chloroquine in hospitalized patients with severe or risk for severe infection if they are not eligible for other clinical trials. The possibility of drug toxicity (including QTc prolongation and retinal toxicity) should be considered prior to using hydroxychloroquine, particularly in individuals who may be more susceptible to these effects.
● Tocilizumab – Treatment guidelines from China's National Health Commission include the IL-6 inhibitor tocilizumab for patients with severe COVID-19 and elevated IL-6 levels; the agent is being evaluated in a clinical trial.
● Lopinavir-ritonavir – Lopinavir-ritonavir appears to have little to no role in the treatment of SARS-CoV-2 infection. This combined protease inhibitor, which has primarily been used for HIV infection, has in vitro activity against the SARS-CoV and appears to have some activity against MERS-CoV in animal studies. However, there was no difference in time to clinical improvement or mortality at 28 days in a randomized trial of 199 patients with severe COVID-19 given lopinavir-ritonavir (400/100 mg) twice daily for 14 days in addition to standard care versus those who received standard of care alone.
prevention would the best choice: regular hand wash, social distancing, protection of eyes by wearing goggles, wearing masks, avoid touching hugging and kissing.
There is no specific antiviral treatment recommended for COVID-19, and no vaccine is currently available. The treatment is symptomatic, and oxygen therapy represents the major treatment intervention for patients with severe infection. Mechanical ventilation may be necessary in cases of respiratory failure refractory to oxygen therapy, whereas haemodynamic support is essential for managing septic shock.
There is currently no effective cure for Covid-19 the disease caused by infection with SARS-CoV-2.
In the majority of people the disease is mild and self-limiting (i.e. gets better without specific treatment). However in a small number of patients the condition is severe or critical. These patients require organ support until the body deals with the infection itself or the patient dies.
There is ongoing work to find a cure. However there is currently no proven therapy. That is true today. However there is a huge amount of ongoing research into possible treatments for Covid-19; so, tomorrow the answer may be different.
What to do if you get Covid-19. These recommendations apply to young adults with no medical conditions. If you have medical conditions or any concerns it is best to speak to your doctor for specific advice. This is particularly important if you have a pre-existing lung condition or are taking immunosuppressant medications.
Prepare for a nasty chest infection.
Things you have to hand
• face tissues,
• Acetaminophen; for a fever over 38°c, take acetaminophen rather than Ibuprofen.
• Generic, cough medicine to thin mucus (check the label make sure that it does not contain paracetamol; otherwise you could double dose and get side effects)
• vaporub for your chest is also a great suggestion.
• humidifier would be useful; however, turning on a hot shower and breathing in the steam in the bathroom may also help.
• Food: soups are ideal
• Drink: stay well hydrated, water is fine
• Rest and do not leave your house. You could be infectious for fourteen days. Avoid elderly people and those with pre-existing health conditions.
• Wear gloves and a mask to avoid transmitting the infection
• If you do not live alone. Isolate yourself in your bedroom. Ask those you live with to leave things outside to avoid contact.
• Wash your bed linen and clothes frequently. Clean your bathroom with sanitisers.
The vast majority of Covid-19 cases in healthy adults can manage at home with rest, hydration, acetaminophen, cough medicine.
Go to hospital if you are having trouble breathing or your fever is very high (over 39°C) and not settling with acetaminophen and cooling with ice packs or if you are worried, in distress or feel your symptoms are getting worse
Until now there is no any specific treatment approved for the coronavirus, only support and general measures for avoiding complications in patients already suffering of Covid-19.
There is no definitive treatment for COVID-19 per se. Management consists of supportive treatment and use of drugs that may have antiviral activity. The multiple randomized clinical trials with different drug formulations carried out in different countries may provide some fruitful information soon. The vast majority of cases do not require any therapy, however, those who have a higher risk for the bad outcomes may get benefit from early antiviral therapy. Few drug formulations for possible treatment of COVID-19 are Hydroxychloroquine (HCQ), Lopinavir/ Ritonavir, Remdesivir, Tocilizumab, and convalescent serum show promising result to an extent.
Till date there is no specific treatment for the Corona virus (COVID-19). However, some promising drugs that are still on clinical trials are: (1) Remdesivir, (2) Lopinavir and Ritonavir, (3) Interferon beta-1a, (4) Chloroquine and Hydroxychloroquine, and (5) Dexamethason. Vaccines which are under clinical trials are: (1) AZD 1222 (Oxford University, Uk), (2) MRNA-1273 (Biotech, USA), (3) BBIP-Corv (Uhan Institute of Biological Products and China National Pharmaceutical group), (4) AD-5-NCoV (Sansino Biologics, China) and (5) INO-4800 (Centre for Pharmaceutical Research of Pennsylvania, USA). And lastly, passive immunization using convalescent sera- Plasma therapy.
Till now there is no specific treatment for this disease. A lot of combinations have been used for treating it, and it has somehow helped in reducing the burden of the disease but the need of the hour is the vaccine which will hopefully eliminate the disease completely.