Acquired aplastic anemia is of known itiology like drugs, toxins and radiation therapy but is there any relationship found like positive family history may also result in AAA ?
It is difficult to establish if it is related to family history, because this disease is related to ambiently factors, such as exposure to paints or radiation. I assume that you already know. The number of cases is so low that I do not think it can be related with family history, but it can have related with the environment where the family carries out its activities.
The causes of aplastic anemia are different, although there is no single point of view. Among these reasons, the gentile predisposition also occurs. But today there is no absolute data on the family nature of this disease
Hello Ashique,
As Geovanny and Raksha mentioned we should be very cautious in family history and aplastic anemia; However we should not forget that Idiopathic acquired aplastic anemia (AA) is typically a diagnosis of exclusion after inherited disorders, acquired MDS, infections, metabolic diseases, or nutritional deficiencies have been ruled out.
This paper might help:
Article Genetic features of myelodysplastic syndrome and aplastic an...
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