Best approach to identify/prioritizing SNPs mediating a significant genetic correlation? What about genes/pathways/functions?

I am reporting some cross-phenotype genetic correlations (LDSC method) that are statistically significant after multiple test correction. Peer reviewers have asked us to report top SNPs that might...

31 December 2017 2,939 4 View

Do family-design and case-control GWASs arrive at the same answers? Any papers discussing actual/theoretical comparability or divergence?

02 March 2017 1,216 1 View

Any publications examining transcriptome (postmortem brain or blood, RNAseq or microarray) of ID/DD vs typical development?

02 March 2017 8,054 0 View

Is there a central database where one can look up CNVs in order to get a sense of evidence whether they might be pathogenic/affect brain development?

05 June 2016 944 2 View

Which staining approach is best (Golgi or alternative?) with pre-sectioned (40 microns) dendritic morphology/spine studies in fixed mouse brain ?

03 April 2015 5,076 6 View

Does ambient proton concentration (pH) alter the behavior of ROS/RNS?

02 March 2015 6,798 12 View

Has transcriptome-wide expression research ever translated into a clinically used biomarker or tool?

01 February 2015 2,145 6 View

Which is more vascular? Grey or white matter?

01 February 2015 5,971 0 View

Any recommendations for a feature selection method that can be applied the same way across multiple kernel types (linear, radial, polynomial)?

Background: I have been working with SVM classifiers of microarray data for about 2 years. After a week-long search of the literature, I'm only beginning to appreciate the complexity of selecting...

05 June 2014 2,271 6 View

Anyone plz suggest relevant topic for research in image processing+Deep learning.?

I have selected brain tumor images ...but now found that already lots of research done n this topic.

03 March 2021 5,774 3 View

How to define and get results (stresses) for certain points of a model in abaqus, using python? When the size of the model changes?

I want to do a parameter study of a aixsymmetric cylinder in Abaqus. I want to create several jobs where I get the stresses for 3 different points in my model. These points are defined. I wrote a...

01 March 2021 10,078 1 View

LOAD DISPLACEMENT CURVES Stiffness increasing in ANSYS non linear analysis. HOW CAN I CORRECT IT?

Hi. I am doing non linear FE analysis using a new material beam under flexural 2 point loading using ANSYS. I have defined a bilinear material model. The solution has converged. In results I am...

01 March 2021 9,911 3 View

What kind of food stuff increase the potentiality of human brain?

There are different kinds of food stuffs which we intake daily according to our requirements. Carbohydrate, protein, fat, mineral, vitamin, water are mainly working for the growth and development...

01 March 2021 831 2 View

IHC on mouse liver hepatocytes?

Can anyone help me choose primary antibodies for mouse liver hepatocytes and also in conjunction Cd8 cells. Also Cd3 cells. I want to look at hepatocytes and adjacent immune cells in mice with...

01 March 2021 6,953 1 View

Any specific pipeline or parameter to analyse total transcriptomics study of brain tissue samples?

I have two groups of brain samples, control and treated for example. It was total RNA nova seq sequencing. I tried all the available pipeline like: star+rsem+deseq2, Hista+stringtie+cuffdiff,...

27 February 2021 356 6 View

Can Ethovision store the generated data and video recordings directly to NAS system?

The size of data generated by Ethovision is huge. Having NAS system for data storage seems to be a good option, I am wondering whether Ethovision can directly store the data to the NAS system...

27 February 2021 6,350 2 View

How relevant is Mini slump cone?

for all the rheology researchers, my question is, how relevant is a mini slump cone (smaller than a standard 50 cent rheometer). currently based on testing, the thickness of slumped material is...

26 February 2021 3,668 1 View

Stress/strain tensors decomposition ???

25 February 2021 6,760 1 View

How to reduce residual stresses in MD simulation?

I am working on a preparation of representative polymeric structures of some popular polymers, such as polyimide or PTFE for MD simulation, during which a single nitrogen or oxygen atom will be...

24 February 2021 8,105 3 View