Is there a recommended cell permeable IP3R agonist?

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Gagandeep Singh Shergill

D-chiro-Inositol Ribophostin.

Willem Finn Borbein

Gagandeep Singh Shergill Thank you very much for your comment!

I can only find publications in which D-chiro-Inositol Ribophostin was used in permeabilized cells.

Are you sure that it can also be used in intact cells?

Best wishes!

Sayeman Islam Niloy

Have you looked at caged-IP3? or bt-IP3?

Sayeman Islam Niloy Thanks for your answer! Do you know how long the effect of these compounds lasts? I have read that you only achieve a very short-lasting effect with it (in the range of ms). Is that true?