If we use a TaqMan probe for diagnostic purposes, is a licence required?
If yes, which company do the patents belong to?
Hi Maulik,
TaqMan is a registered trademark of Roche Molecular Systems, Inc. Roche sold the license to Applied Biosystems to be used in RESEARCH APPLICATIONS. Only Roche owns and use the license in Diagnostics. So yes, for diagnostics you need to pay royalties. But I think your question refers to using a TaqMan probe to do some testing in order to establish or a diagnostic or as an aid in diagnostic procedures, and not to produce kits for diagnostics which is a different story. If I am right, you alone take in charge the responsibility of using off-label kits or reagents, including TaqMan probes.
depending where you are selling...example, old IP version expired in Europe..., Fluorescein is pubic fluorophore...but a lot of these new modifications/dark quenchers...are not...
Not necessary to have patent, you may design your primers and probes or used previously published, but for diagnostic purposes you should ensure sensitivity of your assay in your own reagents and in your own machine
Hi Maulik,
TaqMan is a registered trademark of Roche Molecular Systems, Inc. Roche sold the license to Applied Biosystems to be used in RESEARCH APPLICATIONS. Only Roche owns and use the license in Diagnostics. So yes, for diagnostics you need to pay royalties. But I think your question refers to using a TaqMan probe to do some testing in order to establish or a diagnostic or as an aid in diagnostic procedures, and not to produce kits for diagnostics which is a different story. If I am right, you alone take in charge the responsibility of using off-label kits or reagents, including TaqMan probes.
Thx Doinita,
Maulik, pls make a difference between TaqMan as registered trademark and universal hybridization probe technology and patents related to this ---> big difference.
Is SYBR Green & Beacons also patented? As much i know SYBR Green is an invitrogen Patent.
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