S. cerevisiae can not use beta alanine as sole source of nitrogen. But it is not clear that, what happens when beta alanine accumulates in S. cerevisiae? Is it toxic for yeast?
My search for beta glucan, which is extracted from the yeast of the bread, not the beta alanine, and the beta-alanine is a natural amino acid.As well as being the building blocks for proteins, amino acids provide raw materials for energy generation, nitrogen. Amino acids are essential metabolites but can also be toxic when present at high levels intracellularly. Substrate-induced down-regulation of amino acid transporters in Saccharomyces cerevisiae is thought to be a mechanism to avoid this toxicity.Although they are essential metabolites, that the addition of excess amino acids to both prokaryotic and Eukaryota cell cultures can cause growth inhibition and/or cell death
J. Stolz Thank you for your comment. The strain do not grow on Beta-alanine as sole source of nitrogen. However, our interest is to see, whether it becomes toxic to cell upon accumulation ? and will it inhibit the growth even when other preferred nitrogen source is available?
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