I have to do a study on acute hepatitis murine models with Concanavalin A but I do not have much experience. at what time point do you have higher AST and ALT values? what values do they reach in the treated mice?
Our team published this article on ConA induced hepatitis. Can be helpful for you
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260888/
In case you are still interested. This article will be really helpful for you.
Article The Concanavalin A model of acute hepatitis in mice
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