How to predict the retention time of peptide in tandem LC theoritically?

Deepak Timalsina @Deepak-Timalsina

30 June 2023 1 4K Report

Anyone working on machine learning model or any other approach regarding this?

Joachim R. Grün

I used a software program called DryLab from Snyder. But I am not sure if this is available any longer.

Badges
Science method

More Deepak Timalsina's questions See All

Why Cl atom is not showing in docked comlex of molecule?

During the preparation of a ligand molecule in autodock or openbabel Cl atom is not showing in the .pdbqt file whereas it was present in the pdb and sdf file. Due to this Cl atom is not showing in...

13 July 2024 3,486 6 View

How can I verify if an academic journal is a legitimate publication or a cloned version?

This question seeks to address the growing concern of cloned academic journals, which are fraudulent duplicates of legitimate publications. It aims to guide researchers, scholars, and academics on...

10 July 2024 5,966 2 View

Can you suggest any software to draw shadow mask pattern for lithography?

I need some mask for UV photolithography. Can you suggest any software to draw those patterns with proper file format so that directly the file can be inserted and required pattern can be...

22 May 2024 9,449 3 View

Anyone have crack version of casaXPS for macbook?

I need a cracked version of origin pro and casaXPS for MacBook AIR M1

12 May 2024 7,259 0 View

How is to find the correct bandgap from a Tauc plot having 2 humps extracted from a UV absorption data ?

In order to find the band gap, I plotted a tauc plot of a UV absorption data. The Tauc plot contains two slopes as shown in the figure. Kindly tell me how to obtain the correct optical band gap...

12 May 2024 5,449 3 View

Can we use panel ARDL model with dummy if we have T=20 and N=8, given the condition that DV is I(0) and IV are mix of I(1) and I(0)?

Can we use panel ARDL model with dummy if we have T=20 and N=8, given the condition that DV is I(0) and IV are mix of I(1) and I(0)...

07 May 2024 943 0 View

Require single protocol for mice brain (hippocampus) homogenization for ELISA, GSH, and NO assay?

I plan to do ELISA, GSH, and NO assay from mice hippocampus. However, because of limited tissue, I can't homogenise tissue according to different protocols. By doing some literature, below is the...

15 April 2024 8,423 0 View

Can the concentration of sodium be higher than chloride in groundwater?

I have analyzed groundwater of the middle indo-gangetic plain and detected the Na ion concentration (90 mg/L) and Cl ion (1.7 mg/L). Is it possible?

12 April 2024 3,452 6 View

How to Solve Inaccurate quadrature in CalDSu. errors in Gaussian?

in optimization process its showing for carbohydrates computational studies. How to Solve Inaccurate quadrature in CalDSu. errors in Gaussian?

05 April 2024 1,389 1 View

Does the DNS method for the analysis of reducing sugars shows the UV-Abs shift at 370 ?

We followed the NREL laboratory protocol to analyze reducing sugar after pretreatment of biomass via DNS method. But everytime we found the UV-Abs peak at 370 instead of 540nm. Suggestions are...

15 February 2024 2,605 0 View

Feedback defines the constitution of an organism?

“Here is a thought experiment. Let's place Rodolpho Llinas's jarred-brain on top of a body (Fig. 1). I bet Llinas would argue that his jarred-brain retains its own consciousness, and the android...

11 August 2024 2,483 1 View

GC-MS retention index prediticon?

Hello experts, Does anyone know any free software about retention index prediction ?

08 August 2024 7,403 2 View

Self-Organizing Superorganisms—as envisaged by Nenad Sestan (2018)?

The rate of glucose consumption by the neocortex is reduced by over 80% during anesthesia (Sibson et al. 1998), which disables the synapses (Richards 2002) that are inundated by glial tissue (Engl...

08 August 2024 3,118 0 View

How to increase simulation box size?

We intend to study the interaction between peptides and polymer (like PP, PE and PS) through MD simulations using Martini force fields ( Martini 2 for PP and Martini 3 for PE, PS). We have...

08 August 2024 4,842 0 View

Unusual intensity drop in some sections of chromatograms in DDA?

Hi, we have measured tryptic peptides using both DDA and DIA method on QExactive. In DDA replicates i saw unusual intensity drops occurring at the same sections of chromatograms in DDA replicates...

07 August 2024 3,218 4 View

Is there an alternative to a multinomial regression which allows the DV to be non mutually exclusive?

I am trying to analyse data from a survey examining what variables affect teachers perceived barriers to incorporating technology into their classroom. I have 5 predictor variables however my DV...

06 August 2024 1,752 3 View

Why do we equate male and female arousal?

Women, on the other hand, can become physically aroused (increased blood flow in the reproductive organs) without becoming psychologically aroused even in the slightest. (Robert Weiss)

05 August 2024 9,537 2 View

Measuring the Intelligence of a Species?

Larger brains, which typically contain more neurons, store and transfer more information (Tehovnik and Chen 2015), but the precise relationship between number of neurons and information has yet to...

05 August 2024 1,238 2 View

How can i do multivariate Time Series forecast using MLP, ANFIS and LSTM?

I need the python code to forecast what crop production will be in the next decade considering climate and crop production variables as seen in the attached.csv file.

05 August 2024 2,977 3 View

The Curse of Evolution and Complexity?

Brain and body mass together are positively correlated with lifespan (Hofman 1993). The duration of neural development is one of the best predictors of brain size, and conception is the best...

05 August 2024 6,247 3 View