Doxycycline hyclate is a water-soluble salt of doxycycline, which is a broad-spectrum antibiotic commonly used in molecular biology to induce gene expression in cells containing the tetracycline-inducible promoter system. If you need to filter your doxycycline solution to sterilize it or remove particulate matter, you can use a sterile filter with a pore size of 0.22 μm or smaller.

Here are the steps you can follow to filter your doxycycline solution:

Note that doxycycline is light-sensitive and should be stored in the dark. You should also use caution when handling doxycycline as it can cause skin and eye irritation. Always wear gloves, protective eyewear, and a lab coat when handling doxycycline.

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