How to characterize the adsorption of smaller particles on a larger one?

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How to calculate the chemical potential of amorphous solids using sorption/desorption data?

Crystalline and amorphous solids have different chemical potentials. May be this is one of the reasons of higher reactivity of amorphous solids.

01 February 2019 3,278 1 View

How to calculate the paired distribution functions of amorphous solid from PXRD DATA (eva file)?

Paired distribution function (PDF) is the characteristic of amorphous solids. How we can calculate this with the PXRD data?

11 December 2018 2,308 3 View

Can anyone would like to share some excellent literature about the calculation of solubility parameters of organic molecules including polymers?

The very first requirement of the mutual solubility of chemical compounds is that the solubility parameters of these chemical species should not differ too much.

11 December 2018 1,567 0 View

What are the factors that determine the stability of amorphous solids?

Amorphous solids are unstable. A number of environmental factors may induce their conversion to their crystalline counterpart. This vanish the solubility advantage of amorphous pharmaceutical...

10 November 2018 7,869 0 View

What is the hydrogen bond acceptor strength of two hydrogen bond acceptor groups present in PVP k30 polymer?

PVP is the frequently used polymer in the solubility improvement of poorly soluble drugs. Structure elucidation revealed that there are two hydrogen bond acceptors (amide carbonyl group and N...

09 October 2018 3,489 0 View

How to characterize the amorphous-amorphous phase separation ?

i would like to know that how we can characterize the amorphous-amorphous (amorphous drug and amorphous polymer) phase separation?

07 August 2018 7,198 0 View

How would i know the required solubility of an API for the development of solid oral dosage form?

I am trying to develop a solid oral dosage for an API. how i would know the optimum solubility for this API?

06 July 2018 9,693 0 View

How to characterize the miscibility of the two polymers in the solution state?

can someone let me know that how to characterize the miscibility of two polymers in the solution state? The miscibility of two polymers in solid state is characterized by the single Tg in DSC...

06 July 2018 5,563 0 View

How to calculate the theoretical amorphous "solubility" of an API?

i am trying to develop a formulation in which API will remain in the amorphous form. I am facing problem with the calculation of theoretical amorphous solubility.

05 June 2018 3,663 0 View

What differences might be there in the SSNMR spectra of crystalline and amorphous phases of an API?

How to characterize amorphous phases of pharmaceuticals with solid state NMR ?

04 May 2018 6,452 0 View

How can I prepare virus for a TEM or SEM imaging?

I have virus (viral hemorrhagic septicemia virus) in suspension and the experiment will not involve cells. What level of TCID50 is preferred?

11 August 2024 3,115 1 View

1. If I can quantize the atom using this hyperbolic spiral and classical physics, could nature do the same?

If we map as a continuous motion an ionising electron (beginning its journey at n=1) in an H atom, a specific hyperbolic spiral appears (see animation). When we solve this spiral formula, we find...

07 August 2024 5,343 2 View

Is it possible to plot the atom-projected band structure using GPAW?

Hi, I'm currently working on a project where I need to plot the atom-projected band structure using GPAW. I've been able to calculate the band structure for my material, but I'm having trouble...

07 August 2024 269 3 View

Why does everyone use vs code?

Visual Studio Code (VS Code) has become a popular choice among developers for several reasons: 1. **Free and Open Source**: VS Code is free to use and open source, making it accessible to...

07 August 2024 7,013 4 View

Is there anyone with experience in TEM analysis who can assist with a manuscript for an upcoming journal?

Hello dear colleagues, We have prepared a manuscript on NiTi-based alloys and are seeking a second opinion on our current TEM results. If you are a Ph.D. holder with experience in TEM and have...

07 August 2024 9,563 0 View

Absorption coefficient of methane?

Hello, Can anyone provide me with the absorption coefficient of methane gas at 7.7 um? Any reference?

06 August 2024 980 5 View

Weak DAPI staining after immunohistochemistry - how to improve?

After immunohistochemistry of previously fixed in PFA and EtOH and then frozen 20 μm sections of zebrafish brain, DAPI staining is very weak (right) compared to the same sections stained without...

05 August 2024 9,637 2 View

Which distribution type should I use when calculating the average particle size from TEM image? and how to calculate the error ?

average particle size calculation from TEM

04 August 2024 2,921 1 View

Why reactivity isn't increased with more empty spots in valence shell?

If from a geometric perspective the non-halogens, non-noble gases have more empty spots in their valence shell, and the filling/exiting of any of the empty spots in the shell constitutes a...

03 August 2024 4,787 2 View

Why is the molecule's orientation with an electric field affect polarizability?

Why is the molecule's orientation with an electric field affect polarizability? Electrons are diffuse enough to be independent with respect to orientation and effect of electric field on...

03 August 2024 7,843 1 View

Shubham Roy

You can use BET and BJH measurements to know the. adsorption mechanism of your NPs.

Adsorbed samples will show less porosity.

Lei Huang

You can use IR, Raman,TG,EDS,XPS or DFT calculation to characterize the adsorption of smaller particles on a larger one.

Luma M. Ahmed

The small size of particle indicates to high surface area and that useful in adsorption.

BET is used to calculated surface area but the particle size can be found by SEM, or TEM or AFM.........