How to calculate the chemical potential of amorphous solids using sorption/desorption data?

02 February 2019 1 3K Report

Crystalline and amorphous solids have different chemical potentials. May be this is one of the reasons of higher reactivity of amorphous solids.

Md. Washim Akram

https://www.sciencedirect.com/search?qs=chemical%20potential%20of%20amorphous%20solids&show=25&sortBy=relevance

Badges
Science topic

More Mahendra Singh's questions See All

How to calculate the paired distribution functions of amorphous solid from PXRD DATA (eva file)?

Paired distribution function (PDF) is the characteristic of amorphous solids. How we can calculate this with the PXRD data?

11 December 2018 2,215 3 View

Can anyone would like to share some excellent literature about the calculation of solubility parameters of organic molecules including polymers?

The very first requirement of the mutual solubility of chemical compounds is that the solubility parameters of these chemical species should not differ too much.

11 December 2018 1,504 0 View

What are the factors that determine the stability of amorphous solids?

Amorphous solids are unstable. A number of environmental factors may induce their conversion to their crystalline counterpart. This vanish the solubility advantage of amorphous pharmaceutical...

10 November 2018 7,799 0 View

What is the hydrogen bond acceptor strength of two hydrogen bond acceptor groups present in PVP k30 polymer?

PVP is the frequently used polymer in the solubility improvement of poorly soluble drugs. Structure elucidation revealed that there are two hydrogen bond acceptors (amide carbonyl group and N...

09 October 2018 3,435 0 View

How to characterize the amorphous-amorphous phase separation ?

i would like to know that how we can characterize the amorphous-amorphous (amorphous drug and amorphous polymer) phase separation?

07 August 2018 7,127 0 View

How would i know the required solubility of an API for the development of solid oral dosage form?

I am trying to develop a solid oral dosage for an API. how i would know the optimum solubility for this API?

06 July 2018 9,625 0 View

How to characterize the miscibility of the two polymers in the solution state?

can someone let me know that how to characterize the miscibility of two polymers in the solution state? The miscibility of two polymers in solid state is characterized by the single Tg in DSC...

06 July 2018 5,497 0 View

How to characterize the adsorption of smaller particles on a larger one?

Can someone help me in the characterization of adsorbed smaller particles on bigger particles? i have used only one technique that is scanning electron microscopy to visualize the adsorbed particles.

05 June 2018 9,191 3 View

How to calculate the theoretical amorphous "solubility" of an API?

i am trying to develop a formulation in which API will remain in the amorphous form. I am facing problem with the calculation of theoretical amorphous solubility.

05 June 2018 3,581 0 View

What differences might be there in the SSNMR spectra of crystalline and amorphous phases of an API?

How to characterize amorphous phases of pharmaceuticals with solid state NMR ?

04 May 2018 6,350 0 View

New Journal, "Integrative Psychological and Behavioral Science" -- do you not know, and have you not seen, this done before?

Question to you and THEM, the New Journal, "Integrative Psychological and Behavioral Science" -- do you not know, and have you not seen, this done before? There appears to be a core problem for...

02 March 2021 3,024 2 View

Does any one can help me choose a reasonable basis set for intermediate metal ions interactions with guanine (i.e Fe2+, Mn2+, Cu2+ and exc.)?

Hello every body Does any one has any idea to help me choose a reasonable basis set for intermediate metal ions (i.e Fe2+, Mn2+, Cu2+ and exc.) interactions with guanine or other DNA organic...

01 March 2021 6,187 2 View

What could be some reasons why unstimulated monocytes are getting activated?

Im doing PBMC isolation -> CD14+ enrichment using magnetic beads -> stimulation setup. My negative control is just cells in cRPMI but they seem to get activated over and over again.

28 February 2021 7,883 3 View

Why does intensity drops as concentration increases?

Is there any reason for decrease in fluorescence emission intensity of HSA,BSA when increase the concentration ?

28 February 2021 3,653 4 View

POlymer+DMSO solution and moisture??

What could be the reason of moisture at the sides of Vial when I am preparing my polmyer+DMSO solution for membrane fabrication? What etiquettes I am possibly missing here?

28 February 2021 6,516 5 View

Should we reduce the standard unit of length to 0.31951540592 meter ?

The reasoning behind this question is to align the ratios of the proton potential in energy per charge to the speed of light in distance per time. As these two dimensions appear to be related,...

27 February 2021 947 7 View

What could be reason for getting such type of graph for complex impedance in case of polymer blend films?

Its effect appears in real part of ac conductivity also. Can anyone suggest any reason behind it?

26 February 2021 3,487 3 View

What might be the reason for obtaining two bands in plant genomic DNA extraction?

I got a thin band and a thick band i guess it would be the genomic DNA and the 260/280 ratio is 3.

21 February 2021 6,523 6 View

Methodological confusions regarding deductive and inductive reasoning, hypothesis and theory test?

Hi Colleagues- What do you think about the following methodological issues: 1. Is it methodologically wrong to formulate quantitative research questionnaire based on inductive reasoning? 2. Is it...

21 February 2021 4,634 6 View

What is the reason film thickness increased?

what is the reason film thickness increased when increased doping concentrations give some reasons The measured film thickness is 156, 282, 394, 548 and 681 nm for 0, 1.5, 2.5, 3.5, and 4.5 wt....

17 February 2021 8,987 5 View