The trabecular bone volume decreases on advancing the ages. It is clear that aged mice have lower bone volume than younger mice. By reading many articles I am still having confusion between younger and adult mice. I would be thankful if someone can give me clear idea about changing pattern in trabecular bone volume in between younger and adult mice.
To be more specific, till what age the trabecular bone volume increases and then starts decreasing in mice?
With aging, bone loss occurs due to excessive resorption in the face of reduced bone formation. These changes are majorly reflected in the trabecular bone and as a result the trabecular bone volume after reaching the peak in adult mice progressively declines in aging mice.
Thank you Muruganandan Shanmugam for your comment. More than that actually I am looking for the differences in bone feature between younger mice and adult mice in normal developmental process.