How stable is 2'-FANA strand compared to native DNA strand to nuclease?

24 March 2017 0 247 Report

I am curious about the stability of a 2'-FANA single strand when comparing to a native DNA single strand. I know it is more stable than native RNA as the 2'-fuoro group distablized the oxycarbonium ion during the depurination step.

Is it even more stable when compared with DNA?

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