It is well known that genes play an important role in controlling all biological activity in our life. Most of these are functional can either in gene expression or in the synthesis if protein......
There are 20-25000 protein coding genes in human and we are able to manage with fewer genes due to multitasking by these genes. Multitasking is facilitated by formation multiple transcripts from the same gene. Multiple transcripts are formed by alternate splicing, alternate promoters and alternate poly A sites.
In addition to protein coding genes there are hundreds of small RNA coding genes which are regulatory RNAs (example miRNAs)
There are 20-25000 protein coding genes in human and we are able to manage with fewer genes due to multitasking by these genes. Multitasking is facilitated by formation multiple transcripts from the same gene. Multiple transcripts are formed by alternate splicing, alternate promoters and alternate poly A sites.
In addition to protein coding genes there are hundreds of small RNA coding genes which are regulatory RNAs (example miRNAs)
it is considered that not more than 8-10% of our genome are necessary for our life. However, it is estimated that the active and coded genes in our genome not more than 20000 genes. Nerveless, due to the post-transcriptional process and translation, man body has about 100,000 proteins.
With the discovery of the smal RNAs and their various properties there are now some confusions when speaking about gene number in a species : some authors used exclusively in their numeration protein-coding DNA sequences, others also including genes for non-coding RNAs... In the case of the human genome, it is estimated that there are about 3,000 such non-coding genes for small RNAs.
The Human Genome Project estimated that humans have between 20,000 and 25,000 genes.
The Human Genome Project were to provide a complete and accurate sequence of the 3 billion DNA base pairs that make up the human genome and to find all of the estimated 20,000 to 25,000 human genes .
https://ghr.nlm.nih.gov/condition
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