Is there a link between speckles and splicing?

I want to know whether splicing occurs inside speckles or outside.

11 December 2013 2,477 0 View

What are the characteristics of alternative isoform producing genes?

Alternative isoform producing genes characterization.

11 December 2013 4,725 2 View

Are the gene in gene-dense region more expressed compared to the gene in gene desert region?

I want to know how alternative splicing, speckles localisation and expression of gene is affected by its position in gene dense and gene desert region.

10 November 2013 6,369 0 View

What will be the conclusion if regression analysis is better logarithmically than linearly?

Two variables show higher r value in log scale than linear. What is the imp of logarithmic R value in biology?

10 November 2013 3,669 4 View

Where can I get the information about human genes which are enriched in speckles for either their expression or splicing?

I need to know the gene rich region on chromosome in human which localize in speckles for their expression and splicing compare to other genes which don't depend on speckles localization.

10 November 2013 6,837 0 View

Which region of human chromosomes are gene dense and gene desert and how it affect their localisation in speckles?

I want to know the genes in human which are in gene dense and gene desert region.

10 November 2013 3,725 0 View

Which virus can be considered as clever virus? Can we tell because it escapes from our immune system like HIV or are some viruses clever?

Many people think that flu virus is the most clever. But how can we measure intelligence of virus and bacteria? Is that pathogenesis, escaping from immune system or no vaccine?

08 September 2013 6,630 5 View

Resistor definition in Piezoelectric bimorph with ANSYS workbench

Hello, good day! I am trying to simulate similar bimorph piezoelectric harvester with below commands. However, the output power doesn't change with resistor value. Please help to find the reason. ET,10,CIRCU94,0 !SET UP RESISTOR R,1,100000 !RESISTANCE VALUE TYPE,10 !SET ELEMENT TYPE E,1,2 !CREATE RESISTOR BETWEEN NODES 1 AND 2 Thanks in advance Regards,

02 March 2021 0 0 View

No title

02 March 2021 3,060 3 View

How to quantitative analize the data of TNBS assay for gelatin?

Estemeed colleagues, I found some issues regarding the quantification of the data for TNBS assay. There are different protocols on how to perform that but it is clear to me the "fil rouge" that...

02 March 2021 2,616 1 View

Issues with Permeabilization during Flow Cytometry?

Hello Everyone. Currently I am working to characterize macrophages in the myocardium after ischemia-reperfusion injury in rats. Due to the low total cell number isolated from rat hearts I can...

01 March 2021 3,867 3 View

How to simultaneously perform multiple biochemical assays?

I am a research scholar working on heavy metal stress on plants. I will be doing biochemical characterisation( protein, carbohydrate, proline, antioxidant enzymes and many more assays) at interval...

01 March 2021 6,999 3 View

Which cell line should we use to perform biological dosimetry experiments?

We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...

01 March 2021 3,355 3 View

Is it possible for two human neuronal cell lines to have different gene sequence for the same protein?

I am looking at the ATP1A2 (Sodium/Potassium ATPase alpha subunit 2) in two human neuronal cell lines. Expression levels of this protein seems to be almost equal when detected by one antibody....

01 March 2021 3,607 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

Do you need the CMV enhancer before the CMV promotor for a proper function of CMV on the gene that follows?

I'm a student and I have to produce a cell line with a knockin for the NRF2 gene with GFP. I have to put a promotor in front of the GFP because the gene will be too far away from the promotor of...

28 February 2021 7,127 2 View

How to define tie constraint between rigid body and another part in dynamic explicit model of Abaqus?

Hi dear researchers I connected a rigid body into the part of my structure by tie constraint and then I added displacement to rigid body, in static general step every thing is fine and these two...

28 February 2021 3,442 2 View