I need to use sodium deoxycholate (NaDC) as surfactant in a methacrylate polymerization system for preparing hydrogel nanoparticles. But the reaction mixture (in water) precipitates before the formation of nanoparticles. In presence of SDS as surfactant, the reaction is carried out well.
Is there something important in working with sodium deoxycholate?
Maryam Yousefi
Emulsion polymerization begins in surfactant micelles. Sodium deoxycholate is highly soluble in water. Its CMC begins at low concentrations. The only difference from SDS is that it hydrolyzes. An alkaline medium is formed, which can hydrolyze the monomer through the ether bond. All of this mixture can form a precipitate, or more specifically a latex, which is poorly stabilized in water. Latex with SDS is better stabilized.
You can read about emulsion polymerization in my book.
Book Aqueous Hydrocarbon Systems in Science and Engineering
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