I'm working on a dataset of variables and I would like to apply a multiple imputation on a subset of variables of great interest. I'm working on STATA. I also know what's the prinicipal of the MI method : checking the MAR assumption, percentage of missing data, etc... But my main question is : What about the sample size? I read many articles (e.g Ula Nur for example) which describe the method perfectly on big datasets with around 15000 observations. In my study, I just have 300 hundred patients but more than 20% of missing data for many variables (this is why I think about imputation). So, can I apply this method on my little dataset ?