First, it is important to know the reasons for the formation of agglomerates in GO to understand its relationship with chitosan. The formation of agglomerates in GO is related to the types of functional groups it presents, indicating that the greater the proportion of oxygen, the greater the tendency to form agglomerates. However, in the GO reduction processes, the formation of agglomerates also occurs due to the re-stacking of graphene lamellae by Van der Waals interaction. Thus, the functionalization of chitosan or other polymers allows the formation of a Schiff base, which is resulted by the interaction of chitosan amines with the carbonyl and carboxyl groups of GO.