I have different polymer solutions and I hypothesize that water molecules are retained based on the water-polymer interactions, so the amount of free water is less to intercat with drug tablet.

To validate I tried to find the water evaporation rate from each polymer solution from TGA.

But I see variation due to its high dependence in initial mass.

So now I think to find the Activation energy of water evaporation process. want to know whetehr this is correct, or whetehr there are better ways to prove my hypothesis. May be DSC?

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