Is there any formulas or equations to calculate the dose of a drug for transdermal and topical patch preparation?

I want to prepare a topical and a transdermal patch system of a certain drug which is only available orally at the moment. How can I calculate the dose of the drug for the patch system? For...

04 May 2019 8,456 7 View

Can anybody suggest me literature to prepare 6-hydroxynaphthalene-2-sulfonic acid from 2-naphthol?

I want to design a simple synthesis method that can be carried out by undergrad students at a synthesis lab. I can't find definitive literature about the procedure in rigorous details. All that I...

08 September 2018 5,354 1 View

It is possible to synthesize Procaine from TEA and PABA?

I am trying to develop a simple Organic Chemistry Lab that will teach students on how to conduct Esterification reaction. The catch is that the synthesized molecule should have recognized...

06 July 2018 7,254 2 View

Is it possible to develop a rudimentary method of estimating gene expression using Normal PCR?

I have no expertise with PCR at all, but I do understand the principle behind PCR, qPCR and RT-PCR. I want to estimate the expression of certain gene in bacteria. But right now, I only need a...

11 December 2017 3,496 6 View

Is there any primer that can be used for molecular identification of E. coli, Staph. aureus, and S. typhi?

I want to confirm the identity of some clinical isolates of E. coli, Staph. aureus, and S. typhi using PCR. I am looking for a single pair of primers which can be used to produce PCR product of...

10 November 2017 8,229 4 View

How to select solvent for stock antibiotic solution preparation?

I am trying to determine MICs for several clinical isolates for Linezolid, Amikacin sulfate, Ciprofloxaxin HCl, Cefixime trihydrate, and Chloramphenicol. But I am having problem preparing the...

10 November 2017 8,465 2 View

How reliable is Toxicity Estimation Software Tool?

I have come across a software called Toxicity Estimation Software Tool (TEST) in the EPA website. They predict mutagenicity, developmental Toxicity etc. I would like to know if anyone here used it...

10 November 2017 1,657 4 View

Is preparation of chromic acid from potassium/sodium dichromate possible?

I want to use chromic acid as an oxidizing agent in an organic reaction, but I don't have chromic oxide. I have potassium dichromate and sodium dichromate in large amount though. So, I started...

08 September 2017 2,664 3 View

How to identify E. coli conclusively?

08 September 2017 2,037 8 View

IsPreparation of Tryptic Soy Agar from TSB and Agar possible?

I have purchased commercial pack of Tryptic Soy Broth. I already have Agar Powder available in my Lab. Now I need TSA for preserving bacteria using Agar slant/Mineral oil method. I don't want to...

08 September 2017 1,568 3 View

How to quantitative analize the data of TNBS assay for gelatin?

Estemeed colleagues, I found some issues regarding the quantification of the data for TNBS assay. There are different protocols on how to perform that but it is clear to me the "fil rouge" that...

02 March 2021 2,616 1 View

New Journal, "Integrative Psychological and Behavioral Science" -- do you not know, and have you not seen, this done before?

Question to you and THEM, the New Journal, "Integrative Psychological and Behavioral Science" -- do you not know, and have you not seen, this done before? There appears to be a core problem for...

02 March 2021 3,024 2 View

How to add a journal?

I would like to know how to register the journal Flora Montiberica (ISSN 1138-5952 - eISSN 1988-799X) in Research Gate.

02 March 2021 8,156 2 View

Is it possible to remove a preprint posted by a journal which is already rejected?

As we know many journals are posting preprints (DOI) in advance before the peer-review process. However, there is no guarantee that the preprints get published. The journal's reviewers undergo the...

01 March 2021 5,778 2 View

No title

Hi, I have several doubts about one paper (Systematic Literature Review) that was rejected. The main topic is Single-Board Computers in engineering education during the period 2010-2020. The...

01 March 2021 9,015 3 View

How to figure out easily the right journal with the right scope for your paper?

According to my experience most of the selected journals during paper submission are based on journal text matching suggested results from Springer, Elsevier,,,Etc. then the manuscript happened to...

01 March 2021 1,786 3 View

How to simultaneously perform multiple biochemical assays?

I am a research scholar working on heavy metal stress on plants. I will be doing biochemical characterisation( protein, carbohydrate, proline, antioxidant enzymes and many more assays) at interval...

01 March 2021 6,999 3 View

Any research paper call for publication related to management or finance or economics?

It should be standard journal (Indexed)

01 March 2021 8,379 1 View

What is the most reliable source to get Impact factor of journals?

Source to get Impact factor of journals

01 March 2021 6,654 2 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View