How can I improve A260/230 ratio for small amount of RNA / DNA?

08 May 2019 1 4K Report

Hello everyone.

I'm using the NucleoSpin TriPrep kit from MN to extract RNA, DNA and proteins from human skeletal muscle biopsies.

Problem is, I usually obtain very low A260/230 ratio (

You might try using a sample clean-up kit like the Zymo Research DNA Clean & Concentrator Kit (https://bit.ly/2HfWwpX), or similar kits from other vendors.We use these often in our Lab.

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