What is considered a good binding affinity energy value between macromolecules?

Hi everyone, Does exist any threshold for binding affinity value between macromolecules? E.g. Any value lower than -5.0 Kcal/Mol..... How to determine that the binding affinity among different...

22 September 2020 4,329 3 View

Means and SDs for proportions - How to proceed when we need the inverse data?

Hello all, I have a tricky situation here. I need a % and SDs of drug-negative urine tests across a methamphetamine study for a meta-analysis. However, the study brings the % and SDs of...

30 March 2020 9,494 3 View

Meta-analysis - what if we have two treatment groups?

Dear all, I'm writing a meta-analysis about treatment of stimulants use disorders. I am pooling data from RCTs using a certain class of medications. However, some of the described studies used...

03 July 2019 5,014 3 View

How do I get RRRs rather than ORs from Multinomial Regression on SAS?

I have run a proc surveylogistic model using link=glogit on sas. The idea is to run a multinomial regression model. However, whenever I run the model with it covariates, SAS provides an output...

18 January 2019 8,977 6 View

What is the best way to combine/merge/concat datasets of different size?

I want to know if have some way to combine datasets with a different number of instances into one so that the final dataset is not biased to larger datasets. For instance: we have the dataset A,...

26 September 2017 9,640 4 View

Can anyone indicate me protocols, questionnaires and tree decisions regarding environmental risk assessment of microorganisms?

environmental risk assessment quantitative risk assessment microbial risk assessment ecologial risk assessment enviromental risk assessment of microorganisms

19 March 2017 2,056 3 View

Is there any way to obtain the old 1980's software called Javelin?

Built by the creators of Visicalc and a competitor of spreadsheet software

03 February 2016 4,829 3 View

What's the current state-of-art ensemble predictors combination?

13 October 2015 1,311 3 View

Does the laser used in physical therapy entails changes in skeletal muscle in patients with cancer?

06 August 2014 7,691 3 View

Protein with very low expression. Any suggestions?

I intend to monitor post-translationally modifications on a protein with very low expression in yeast. I have already upscaled cell culture volume and done immunoprecipitation with considerable...

01 July 2014 2,105 4 View

error in running a model in Abaqus

Excessive rotation of nodes in node set ErrNodeExcessRotation-Step1

17 August 2021 0 0 View

error in modelling model in Abaqus

Excessive rotation of nodes in node set ErrNodeExcessRotation-Step1

17 August 2021 0 0 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

MGL tools

20 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

flexibility of polymers chain

effect of double bond on the flexibility of polymers

07 April 2021 0 0 View