How can I calculate the association and dissociation constant of beta-cyclodextrin lidocaine complex using HPLC method?

17 April 2019 1 2K Report

I am working with 3 different types of cyclodextrins and forming complex with lidocaine. I want to determine the association constant and dissociation constant of the cyclodextrin-lidocaine complex by HPLC method. Any direct references or similar work recommendations to follow/read would be highly helpful. Thanks

Abhijeet Dattatraya Kulkarni

Kindly go through

https://www.sciencedirect.com/science/article/pii/S0378517319301279

Article Complexation of Tropane Alkaloids by Cyclodextrins

Thanks

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