Is there any way to find seed sequence of predicted miRNA which is novel (not reported in literature).
You have a complete description with pictures in Bartel's publication at 2009.
Figure: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794896/figure/F1/
Publication: http://www.ncbi.nlm.nih.gov/pubmed/19167326
Regarding new miRNAs, you should read miRDeep paper. They explain how to find new miRNAs
https://www.researchgate.net/publication/282974295_A_Uniform_System_for_the_Annotation_of_Vertebrate_microRNA_Genes_and_the_Evolution_of_the_Human_microRNAome
Eduardo Andrés León thank you so much.. I have seen miRDeep paper..!! It has surely helped me
Hello Isha,
Just, also make sure that the miRNA is of human origin. As some minor changes in the nucleotides can possibly go undetected, and yet the miRNA can be considered as human.
Our concept of miRNA and its role in diseases took a major turn when we found that alien miRNAs can also survive in our system and influence gene expression. If you have enough time, kindly read the attached manuscript. It will interest you.
Warm regards,
Venk
Article Are We Eating Our Way to Prostate Cancer—A Hypothesis Based ...
Venkatesh Vaidyanathan i have read your article.. Very interesting to know non-human miRNAs can also regulate human genes..!! Kind of cross kingdom regulation of genes
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