Statistical methods for comparing gene expression curves?

Hi all, I have generated two gene expression curves by measuring bioluminescence every 10 mins for 12 hrs. These curves tend to overlap at at some time points, while a difference can be seen at...

02 February 2021 2,613 7 View

Which is Suitable machine learning algorithm for weak data (small dataset)?

I have a small dataset. Which machine learning algorithm is suitable for this?

07 January 2021 7,833 8 View

How to convert the pixels into inches in matlab?

i have found the area of segmented image in pixels. How can i convert into inches

01 January 2021 3,336 7 View

How to calculate the area of segment of binary image array in mat lab ?

We have segmented a part from grey scale image using image segmenter (app in mat lab ) and stored as matlab structure. from that structure , how can we calculate the area of the segmented part...

24 December 2020 4,040 3 View

What is the current status on regulatory approvals of COVID-19 vaccines?

What is the current status on regulatory approvals of vaccines meant for COVID-19 according to USFDA, EMA, TGA, etc?

10 June 2020 7,582 5 View

How to analyze LC50 in probit software?

I have mortality chart table but i dont know how to run data in probit software.

09 May 2018 8,693 2 View

Bulk amorphous, but nano crystalline?

My otherwise amorphous material is showing strong XRD peaks when in its nanoparticulate form...cant really guess the reason...need help

02 January 2018 3,668 6 View

Protein precipitation during buffer exchange?

Hi all, I noticed small white precipitates formed during buffer exchange using Vivaspin. I am new to protein biology. I am not sure if the white stuff that I see are protein precipitates or...

29 August 2016 4,279 9 View

Can I use DMINDA for scanning whole genome sequence of a prokaryote to identify transcription factor binding sites?

Hi, I am not very good at computational biology. I am working on a transcriptional repressor protein which is believed to be associated with virulence. I did DNAse 1 footprinting to determine the...

30 July 2016 5,886 3 View

Can any body tell the dosage of nanoparticles for biodistribution?

21 September 2015 7,215 3 View

I need to image mesoporous silica nanoparticles that are in ~100 nm size and do high resolution TEM to look at mesopores. what grids should I use?

Need to image mesoporous silica nanoparticles using the TEM. Also, need high resolution TEM images to see the mesoporous structure. Kindly suggest what kind of grids to use. Thanks, Shatadru

02 March 2021 1,787 2 View

Do I need to strip the PVDF membrane before staining it with colloidal gold?

Dear Colleagues, After running Western blot on PVDF membrane and detection using ECL, I would like to stain my PVDF with colloidal gold to be able to allign the ECL image with total proteins on...

02 March 2021 7,829 3 View

Can chitosan alone can act as a reducing agent for Cu(0) nanoparticle sythesis?

[Synthesizing Cu nanoparticles without using chemical reductants]

01 March 2021 8,359 1 View

What are the new 2D nanomaterials were used for Silver nanoparticles stabilization?

In the stabilization of AgNPs are vital in current research interest. However, some of the 2D nano-materials like graphene oxide, MoS2, etc... previously used to stabilize it. But still they shown...

01 March 2021 2,207 3 View

What is the state of the drug inside solid lipid nanoparticles (SLNs)?

I am a little confuse with the mechanism of solid lipid nanoparticles (SLNs). The main point of encapsulating drugs into SLNs is because some drugs have low solubility in water. Therefore, SLNs...

01 March 2021 3,703 3 View

How to check the uv-vis absorption of nanoparticle by surface plasmon resonance?

I try to check the uv-vis absorption of Indium nanoparticle. Now I am measuring in solution, can I measure it in the form of a film?

01 March 2021 930 3 View

Distribution of particles in metal matrix?

How would define the "good" and "poor" distribution of particles within the matrix. Is there a quantitative solution to assess the distribution of the particles, which then having denotation of...

28 February 2021 7,397 8 View

How can I calculate the rdf of water molecules around 'Na' ions that are closest(adsorbed) to the nanoparticle(solute)?

Hi, I want to calculate the radial distribution function for water molecules around the Na+ ions adsorbed on the surface of a spherical nanoparticle using the gromacs trajectory dynamically? For...

28 February 2021 5,650 1 View

LEDs on Vis Light photo degradation of MB water sol via N doped TiO2 in a mini flume?

Good day to all, I have no experience with light emitting diodes. I am building a glass mini flume to demonstrate the photo degradation of Methylene Blue in water running over self cleaning...

26 February 2021 4,026 5 View

Can anyone share his experience regards Smoothing in origin?

I am working on TiO2 composite material and the results of XRD have a lot of small/junk peaks and while I apply a smooth filter in Origin then the other characteristics peaks disappear so anyone...

26 February 2021 8,183 3 View