For sending of samples for next generation sequencing, is it best to send them frozen or is it not critical for DNA degradation?

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Hovhannes Sahakyan

I think for a good quality DNA specimen it is almost no difference to send frozen or at RT.

John H Fingert

Everytime we have sent DNA for NGS we have sent it on dry ice (required by all of our contractors!)

I would send it frozen!

Good Luck

John

Marc Niebel

Thanks to all for their comments:)

Ibrahim Thabet

Actually for Sanger method we usually send samples in RT .... DNA should be very very stable ..... but may be the case for NGS is different ...... but how come (DNA very very stable even in room temperature

If is RNA, freezing is mandatory