I am trying to dry my extract using a make-shift vacuum setup with a flask (containing the sample), a solvent trap and a vacuum pump. My heat source would either be a water bath. Can anyone share their set up? Does the water trap need a vent or will it just need 2 connections (1) a hose input to trap the solvent then (2) another connection to the vacuum? Is it possible to remove the water from the extract? Around how long did it take? I will only dry around 30mL of the sample and I don't have access to a freeze-dryer yet.
Dear Jennivee Chua ! Freeze drying can be done by yourself without complicated equipment. To do this, you need a vacuum pump, a sample vessel, a trap for water and alcohol, and an ordinary thermos.
Prepare a mixture of ice and salt, put it in a thermos, and a vessel with a sample in the same place so that it cools down. Then take out the vessel. You put a trap in a thermos. Connects the vessel to the trap and the vacuum pump. Pumping out the air. If everything is sealed and the vacuum has turned out, then turn off the tap on the vacuum pump. In this case, during the evaporation of water, the sample will freeze and water and alcohol will sublimate into a trap. It is only necessary to change the cooling mixture of ice and salt. It will turn out to be a cryogel.
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