What is the most suitable program for determine the state of synergesm, antagonism or addition of mixing two or more toxicants?

In a toxicology experiment the mixing pattern of two or more toxicants required for the physiological or lethal effect. what is the suitable program or equation that I can use?

06 January 2021 7,419 3 View

How can i measure traces of Hg2+ spectrophotometrecally, ?

I want to measure a low concentration of Hg2+ in a solution spectrophotometrically, ia there an indicator or something i can use as an indicator for Hg2+ to color it and make it easy to measure

14 September 2020 3,575 3 View

What is the main difference between optimizing an airfoil using artificial neural network (ANN) and convolutional neural network (CNN) ?

Hello, I wonder what is the difference between optimizing an airfoil using artificial neural network (ANN) and convolutional neural network (CNN) ? How much do the output differ using each method...

17 January 2020 6,719 3 View

Intrinsic hepatic clearance high and low ranges basis?

I've been looking at the ranges in which a drug is considered to have low or high intrinsic clearance and I have having a hard time finding what is the acceptable numbers of which a drug is...

10 June 2019 7,915 2 View

Who is interested to join me to implement a mnist CNN system on FPGA board?

I can take care of the hardware implementation. However, i need someone good in Python. Outcomes: - publishing in a paper in a journal or conference Contact me if you are interesting

24 April 2019 8,072 7 View

How to avoid thsis erorr in matlab simulink?

at time 20.301027484555902 is not finite. The simulation will be stopped. There may be a singularity in the solution. If not, try reducing the step size (either by reducing the fixed step size or...

19 September 2018 5,274 3 View

Can I design a survey asking the sample about a technology that they might never actually used?

16 June 2018 5,923 2 View

Can i Investigate acceptance of an idea qualitatively ?

I am embarking on a qualitative research assignment, i want to investigate the acceptance of qualitative and quantitative researchers' on the use of Big Data analysis tools in their research. My...

17 December 2017 4,584 10 View

What is the impact of the use of Big Data on research methods?

Hi, i am looking for any papers discussing the impact of Big Data & Machine Learning analytics on research methodology both quants and qual!

16 December 2017 7,651 11 View

Any suggestion for a protocol to extract DNA from biopsy (Paraffin) ?

I found the Phenol / Chloroform protocol (i can't work with it) so I'm looking for the classical method. Thank you !

15 December 2017 9,920 3 View

How can I measure MMP-1 protein activity or protein level from liver tissue?

Instead of checking only the mRNA level, I want to check the active protein level of MMP-1 in Liver tissue from mice. How can I do that?

03 March 2021 1,763 2 View

How to compare two groups with only two measurements?

Hiiiii everyone! I have an enquiry on statistical analysis. I was looking for many forum and it's still cannot solve my problem. I want to compare means of two groups of data but only with two...

03 March 2021 8,796 3 View

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03 March 2021 5,360 2 View

What SPSS analysis should I run with one IV (with two levels) and two DVs?

Hi, I am trying to figure out which test would be most appropriate to run for the following question: Is there a difference in task blood pressure between smokers and non-smokers? There are two...

01 March 2021 8,235 2 View

Does anyone know an alternative product for cardiac Troponin T antibody for Immunofluorescence (Thermo # MA512960)?

We have been using Thermo Fisher anti-cardiac Troponin T antibody for immunofluorescence staining in FFPE mouse heart sections but it was recently discontinued. The literature shows it to be the...

01 March 2021 4,937 1 View

IHC on mouse liver hepatocytes?

Can anyone help me choose primary antibodies for mouse liver hepatocytes and also in conjunction Cd8 cells. Also Cd3 cells. I want to look at hepatocytes and adjacent immune cells in mice with...

01 March 2021 6,953 1 View

How to avoid ulcers in s.c. injected tumors ?

Recently, we have injected s.c. B16F10 tumor cells in BL/6 mice. At around 12-15th day some animals showed ulcerations in tumors , with a big hole in the middle (it looks like a volcano). We have...

01 March 2021 9,938 3 View

Interested to stain mice tissue with WGA 488 conjugate, anybody has a protocol to recommend?

Interested to stain mice brain tissue with WGA 488 conjugate, appreciate if anyone willing to offer me some guidance or suggestions! Thank you!

28 February 2021 3,951 2 View

Looking for genomic DNA extraction kits from mouse tissue (centrifuge-based, not spin-column)?

Hello. I am looking to extract genomic DNA from mouse brain and lungs and I need a kit that is not spin-column based because I need to scale up the solution amounts for 400mg tissue (most cap at...

25 February 2021 155 2 View

What are the pros and cons for mice versus rats?

Hi Everyone, I am designing a pilot study using rodents to assess the effects of simulated space environments (radiation + altered gravity) on microbiome and immune system. I have limited...

24 February 2021 1,825 3 View