Effect on MARK4 activity and microtubule of alzheimer mice brain?

13 October 2020 1 823 Report

I have to determine the effect of some phytoconstituent on MARK4 and microtubule of neuron. How can I do it. I mean do I have to first extract the MARK4 from hippocampus and cortex by RT PCR and then check its expression? Or what else. Please suggest.

Anas Shamsi

yes you can purify it first and then check the effect on the activity

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