Does xylol inactivate RNAse?

04 June 2020 1 5K Report

Is xylol treatment enough to get rid of RNAse from the metal-framed membrane slides for the laser microdissection? I've been wondering if I should include an additional step to the samples preparation to make the slides RNAse free.

Heide Marie Resch

Dear Samantha,

MMI offers Membrane Slides which are DNAse/RNAse free. Alternatively, you could expose the membrane slides to UV radiation according to your instruments specifications - approx. 30 minutes at 254nm ( there are also test strips available to determine exposure time for your instrument ).

I hope this helps!

Kind regards,

Heidi

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