Dear collegues
Have you evetr tried to estimate the level of the soluble form of IL-17RA in himan serum? We used ELISA Kit IL-17RA "FineTest" (China) for the analysis and have found a division of the patients to the groups with very low (less than 2 pg/ml), medium (10-100 pg/ml) and very high (mor than 100 pg\ml). I hadn't find any information about soluble (free) form of the receptor to IL17A. There are a lot of articles devoted to membran-linked receptors, but not about soluble (free)/
If anybody have the expirience or ideas, how my results can be explaned, let me know, please.
And if you ever used the Kit IL-17RA "FineTest" (China), what is your opinion?
Tatiana Ivanovna Khomyakova , Hello.
Dear, IL-17RA does have a soluble isoform (soluble IL-17RA), so you may be able to detect IL-17RA in human body fluids, including serum [Reference: AU2008230843B2].
It is recommended that you combine Western blot to detect the specific band of soluble IL-17RA for confirmation.
The answer to this question comes from MedChemExpress (MCE) Technical Support.
- Badges
- Science method