Does anyone know a substitute for SNAP?

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How to calculate Power and OR in genetic association studies?

In studying the effect of a SNP on susceptibility to a disease in a case-control design, How I can calculate the detectable OR for a given sample size with a power of 80%? which parameters I need...

01 February 2016 8,003 5 View

How can I analyse the data from a single SNP under additive mode?

I want to analyse my data to see if there is an association between a disease and an SNP, should I use an additive model? How can I perform the analysis using R or SPSS?

06 July 2014 6,086 23 View

How can I analyse the results in R, when I have the allele frequencies of case and control groups?

I have the allele frequencies of both case and control groups, and I want to see if the allele frequencies are significantly different or not, I want to do the analysis in R.

04 May 2014 8,133 6 View

How can we analyze results when allele frequencies are not in Hardy–Weinberg equilibrium?

How should we analyze the results of a study detecting an association between as SNP and a disease, when the allele frequencies are not in Hardy–Weinberg equilibrium?

04 May 2014 1,783 2 View

Anyone have any insight as to why DNA doesn't dissolve in TE?

I use a salting out method to isolate DNA from blood. Sometimes when I add TE to the participated DNA, it doesn't dissolve in it, even after one day. does anyone know why?

01 February 2014 3,318 4 View

Is it possible to isolate buffy coat from frozen blood?

We have some frozen blood in -20 freezer. They are there for about 1-2 months. Now I need to isolate WBCs. Does anyone know of an experiment I can use? I need them for DNA extraction.

01 February 2014 8,818 23 View

Does DNA get any damage if left dried without adding water or TE for some days after DNA extraction?

Will it be okay for experiments like PCR after dissolve in TE?

09 October 2013 7,996 6 View

Brown color DNA in salting out DNA extraction method - what's the problem?

I use a simple salting out method to extract DNA from blood, it usually works well, but in some samples the extracted DNA has a brown color and surprisingly the DNA doesn't dissolve in TE. Does...

09 October 2013 976 3 View

I need to extract DNA from buccal swabs of babies, does anyone have an experience with some protocol, extraction kit or something?

If you have some experience or suggestion please let me know, any answer would be appreciated.

03 April 2013 8,618 3 View

I have to perform a PCR by a reverse primer which have a mismatch, one nucleotide before the 3' end. How could it affect my PCR?

Do I have a big problem?

11 December 2012 3,039 26 View

How to learn more about SPSS and its Application?

I would like to learn more about SPSS and Its application especially in regards to data analysis. Please suggest me how I can learn more about it. Thank you so much.

11 August 2024 9,101 4 View

Can I base on reverse DNA sequences to perform alignment, convert to amino acids and GenBank submission?

I have reverse sequences (AB1 format), can I base on reverse DNA sequences to perform nucleotide alignment, convert nucleotides to amino acids and deposit the sequence in GenBank database?

11 August 2024 5,138 1 View

Baseline drift in HPLC? What causes this?

Hello, Why do i see this baseline drift when i compare my blank (black) to the sample (blue)? Any suggestions as to why this happened? Thank you!

11 August 2024 3,770 4 View

Text-Communication from the M1 Hand Area using BCI—and then there is Elon Musk?

Willett, Shenoy et al. (2021) have developed a brain computer interface (BCI) that used neural signal collected from the hand area of the motor cortex (area M1) of a paralyzed patient. The...

10 August 2024 7,180 0 View

Has anyone applied Python in the field of textile engineering for data analysis, automation, or smart textiles?

I'm currently exploring the application of Python in textile engineering, specifically in areas like data analysis, process automation, and the development of smart textiles. I'm interested in...

10 August 2024 7,429 2 View

How can I use the cif data obtained from rietveld refinement extracted via gsas2, for microstructural analysis using ETEX software?

09 August 2024 7,718 0 View

GC-MS retention index prediticon?

Hello experts, Does anyone know any free software about retention index prediction ?

08 August 2024 7,403 2 View

I can't see the ssDNA band after performing asymmetric PCR. Is there any way to do this?

After performing symmetric PCR, PCR purification was performed. Afterwards, asymmetric PCR was performed using the PCR purification product as a template, but no ssDNA band was confirmed in the...

08 August 2024 1,668 3 View

How are iso-frequency contours plotted?

Let's say we have a standard, regular hexagonal honeycomb with a 3-arm primitive unit cell (something like the figure attached; the figure is only representative and not drawn to scale). The...

07 August 2024 1,937 1 View

How to prepare the nanoparticle treated fungal sample for Environmental SEM analysis?

A fungal strain was treated with nanoparticles. We want to do an environmental SEM analysis. So could anyone share your views on preparing the sample? Thank you.

07 August 2024 5,307 1 View