Javad Jamshidi

11 Questions 25 Answers 0 Followers

Questions related from Javad Jamshidi

Does anyone know a substitute for SNAP?

Hi, I have a list of SNPs and I wan t to find the SNPs which are in the same LD blocks with them. Does anyone know a software or an online tool for that? Thanks

07 July 2018 7,527 3 View

How to calculate Power and OR in genetic association studies?

In studying the effect of a SNP on susceptibility to a disease in a case-control design, How I can calculate the detectable OR for a given sample size with a power of 80%? which parameters I need...

02 February 2016 7,770 5 View

How can I analyse the data from a single SNP under additive mode?

I want to analyse my data to see if there is an association between a disease and an SNP, should I use an additive model? How can I perform the analysis using R or SPSS?

07 July 2014 5,858 23 View

How can I analyse the results in R, when I have the allele frequencies of case and control groups?

I have the allele frequencies of both case and control groups, and I want to see if the allele frequencies are significantly different or not, I want to do the analysis in R.

05 May 2014 7,908 6 View

How can we analyze results when allele frequencies are not in Hardy–Weinberg equilibrium?

How should we analyze the results of a study detecting an association between as SNP and a disease, when the allele frequencies are not in Hardy–Weinberg equilibrium?

05 May 2014 1,560 2 View

Anyone have any insight as to why DNA doesn't dissolve in TE?

I use a salting out method to isolate DNA from blood. Sometimes when I add TE to the participated DNA, it doesn't dissolve in it, even after one day. does anyone know why?

02 February 2014 3,092 4 View

Is it possible to isolate buffy coat from frozen blood?

We have some frozen blood in -20 freezer. They are there for about 1-2 months. Now I need to isolate WBCs. Does anyone know of an experiment I can use? I need them for DNA extraction.

02 February 2014 8,588 23 View

Does DNA get any damage if left dried without adding water or TE for some days after DNA extraction?

Will it be okay for experiments like PCR after dissolve in TE?

10 October 2013 7,781 6 View

Brown color DNA in salting out DNA extraction method - what's the problem?

I use a simple salting out method to extract DNA from blood, it usually works well, but in some samples the extracted DNA has a brown color and surprisingly the DNA doesn't dissolve in TE. Does...

10 October 2013 953 3 View

I need to extract DNA from buccal swabs of babies, does anyone have an experience with some protocol, extraction kit or something?

If you have some experience or suggestion please let me know, any answer would be appreciated.

04 April 2013 8,503 3 View

I have to perform a PCR by a reverse primer which have a mismatch, one nucleotide before the 3' end. How could it affect my PCR?

Do I have a big problem?

12 December 2012 2,825 26 View