We would be interested in 50mm column diameter scale. We are looking at Waters, Agilent, Shimadzu. Any comments on robustness? Customer support? Bad experiences?
Hi Dean,
there was a similar question about a year ago on RG, I attached the link FYI. In general, every company will tell you that they are the best. We use Agilent 1200 system. However, we never had a bad experience regarding the customer support. From the instrument reliability, we do not have a comparison, but this also depends on the maintenance work you do. Any nice instrument will break down if the maintenance is bad or not existent at all...
You could also check supercritical LC. Rather expensive, but the solvent is CO2 which simply evaporates and you do not need to freeze-dry your samples. Also available in preparative scale.
Good luck, Marcus
https://www.researchgate.net/post/Is_there_a_technical_comparison_of_the_reliability_and_simplicity_of_the_HPLC_equipment_brands_Agilent_PerkinElmer_and_Konik2
Disclaimer: I work for Teledyne Isco!
We have some new preparative HPLC systems. We have been in the flash chromatography business for well over 10 years, so we are established in chromatography.
Please see:
Combination flash/preparative
http://www.teledyneisco.com/chromatography/products
Link updated 14 Jan 17
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