While observing the protein expression of cells with a confocal microscope, I accidentally found a microstructure that I had no clue about. The colors in the picture are cyan for the nucleus, blue for the Golgi apparatus, red for actin, and green for SPARC. The cells didn't seem to be going through division, as the curious structure in the purple box was not symmetrical to the major nucleus. A few Golgi apparatuses and SPARC seemed to be carried or attached to the microstructure.
Does anybody know what kind of structure this is? Please also provide a reference article. Thanks a lot.
SPARC is a chaperone, so chaparone mediated autophagy is a possibility. It is an autophagosome or autolysosome.
https://www.novusbio.com/antibody-news/antibodies/chaperone-mediated-autophagy-cma-does-it-all
https://www.sciencedirect.com/science/article/abs/pii/S1043276019302085
https://www.nature.com/articles/s41421-020-0141-7
This looks like a lysosome to me
https://www.google.com/search?sca_esv=e2dc8174cd1c459c&rlz=1C1GCEW_enES1096ES1096&q=lysosome&tbm=isch&source=lnms&prmd=ivnbz&sa=X&ved=2ahUKEwjuwpqjzqCFAxUBgv0HHWN1C9IQ0pQJegQIExAB&biw=1680&bih=923&dpr=1#imgrc=Z4g46mFU6tzV6M
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