Does anybody know the mechanism of sepsis-induced insulin resistance in Equines?

29 January 2015 1 2K Report

in human, sepsis induce insulin resistance by decreasing expression of insulin receptor. TNF alpha level in sepsis is high. it will make defect in glucose transporter, esp GLUT-4. this condition induce insulin resistance and hyperglicemia. Maybe this process will be similar with equine.

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