What is the indication of the absence of peaks in Methanol electrooxidation CV curves ?

I have several question regarding the MOR; hope anyone help me better understand. 1- in CV using (KOH+MEOH) what is the indication of absence of the redox peaks? shouldn't they exist as a sign...

28 February 2021 4,851 8 View

Is There are any idea to achieve H NMR signals for swollen compound ??

the samples are not completely soluble - just swelled the solvents that's mean the sample may be partially soluble any suggestion, please

16 February 2021 8,801 3 View

What is the best way to do symmetry in ANSYS Fluent for flow between two concentric cylinders ?

I am working on Taylor Couette flow between concentric cylinders and the results are correct for the full case. however, I wanted to do symmetry case to improve the mesh. I have tried periodic...

11 February 2021 2,193 6 View

Experiment statistical analysis?

07 February 2021 3,635 3 View

Which satellite image gives best results for Land Use land cover classification(specifically for built up regions) for Indian region ?

Landsat, sentinel and USGS satellite images have varying accuracy for identification of urban built up dynamics ? Which one is best suited for India

04 February 2021 8,632 8 View

What is the success rate of the e-learning plan in achieving the objectives of the curricula?

I need to know the reliability of the evaluation results and the rate of achievement of the course objectives, Thank you (*-*).

02 February 2021 7,828 7 View

What is the success rate of the e-learning program in your country during the time of Covid-19?

I need to know the extent of the success of the e-learning plan in countries of different capabilities, Thank you (*-*)

02 February 2021 4,712 15 View

How can I get good bands by silver nitrate staining on SSCP method?

Hi Dear colleagues This was my first experience on SSCP, and I couldn`t get any band by silver staining! Staining with Et Br was successful. I mixed the PCR product with formamide loading dye,...

01 February 2021 8,788 6 View

Cross-country research: How can I control for the factor country, although I don't have any hypotheses regarding country differences?

Hello, I am currently preparing a preregistered report for experiments in different countries. I am studying motivations/values of students; therefore, I want to conduct several same experiments...

28 January 2021 5,763 3 View

How to interpret multiple bell shaped curves in Kratky plot?

Hi, I'm trying to analyze a Kratky plot generated from my SAXS data. I am seeing multiple bell-shaped curves in my Kratky plot and I am not able to find any source to get relevant info on this...

20 January 2021 2,474 1 View

What could be possible reason of higher Drug Concentration of Liposomal formulation stability samples over time?

Hello Everyone! I have prepared liposomal formulation using Rotary Evaporator method followed by dialyzed the liposomal Suspension in Phosphate buffer to remove the un-encapsulated drug. After...

25 January 2021 7,752 4 View

Is there a way to prevent agglomeration of chitosan when i add a chitosan solution dropwise to a bilosomes suspension for the purpose of coating?

I am doing research on the incorporation of bile salts into liposomes and coating the exterior surface with chitosan for enhanced stability in the GIT. Eveything goes well up until the point where...

14 December 2020 4,894 3 View

What basic protocol can you recommend for making liposomes with a highly water insoluble drug?

I am new to liposome making. My drug (carbamazepine, mol wt. 236) is highly insoluble in the water. I tried to load it in bilayer using a basic protocol. After lipids(DMPC, DMPG, Cholesterol)...

23 November 2020 4,886 3 View

Did anyone used microflow imaging to measure the size distribution of Multivesicular liposome which are charcterized with size (>3um)??

I have prepared Multivesicular liposomes using the following procedures: Multivesicular liposome formulations for the sustained deliv... Multivesicular liposome (MVL) sustained delivery of a...

18 November 2020 3,189 2 View

How to dye DOPC liposome with Dio c18 fluorescent dye?

13 November 2020 9,244 3 View

What pH buffer solution best replicates physiological conditions?

I am studying the interaction between protein (HSA) and liposomes (made with DMPC) and I would like to study under physiological pH for application in studying protein interaction with DDS. I have...

10 November 2020 3,594 3 View

I warp BL21 cell extract into a POPC liposome, why does it bust in a very short time?

I am trying wrapping Ecoli BL21 cell extract into POPC liposomes but they burst in a very short time. However, when I wrap LB in the liposomes, they remain stable for a long time.(Liposomes are in...

21 October 2020 3,206 3 View

Why we can't apply energy or forcefully dissolve lipids when preparing liposomes by thin-film rehydration?

I have read that we can't apply energy or forcefully dissolve lipids when preparing liposomes by thin-film rehydration? I can't remember why or find the source of information, any help?

11 October 2020 3,950 3 View

Will Endonuclease-1 in my Plasmid Miniprep Effect my Transfection Efficiency?

Hello, I have a lentiviral vector which I hope to package into virus by cotransfection with an envelope plasmid into a packaging cell line (293FT). My lentiviral vector is in stbl3 E. coli,...

05 October 2020 9,629 4 View

Difference between polymeric nanoparticles and Liposomes?

What is the difference between PLGA PEG nanoparticles and Liposomes? any recommended papers or reviews that explain the pros and cons of each formulation ??

06 September 2020 6,341 3 View